1 Result for "

Arg279

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Arg279" in MCE Product Catalog:

Cat. No.: HY-187539S
CAS No.: 3085716-86-2
Research Areas:  

Cardiovascular Disease

IPR agonist-1 is a prostaglandin-based IP receptor agonist. IPR agonist-1 binds to the IP receptor, forms hydrogen bonds with Tyr75-Ser168-Arg279, and undergoes π-π stacking with Tyr281, thereby triggering downstream signaling pathways. IPR agonist-1 inhibits ADP (Adenosine 5'-diphosphate) (HY-W010918)-induced platelet aggregation in rabbit platelet-rich plasma. IPR agonist-1 can be used in the research of pulmonary arterial hypertension .
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