22 Results for "

Azide-PEG2000-azide

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "Azide-PEG2000-azide" in MCE Product Catalog:

Cat. No.: HY-140664
Research Areas:  

Cancer

Azide-PEG2000-azide is a PEG derivative. It is a click chemistry reagent. Containing the Azide group, it can undergo a copper-catalyzed azido-azynylene cycloaddition reaction (CuAAc) with molecules containing the Alkyne group. It can also undergo a ring-strain-driven alkyne-azido cycloaddition reaction (SPAAC) with molecules containing the DBCO or BCN groups.
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1 Cited Publications
Cat. No.: HY-P10896
CAS No.: 1446005-10-2
Target:  

Bombesin Receptor

Research Areas:  

Cancer

NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with 111In and 68Ga for prostate cancer imaging studies using PET and SPECT/CT .
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Cat. No.: HY-W440832
Target:  

Liposome

Research Areas:  

Others

DSPE-PEG2000-azide is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery . DSPE-PEG2000-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-P10303
CAS No.: 2767993-86-0
Synonyms: Cyclo[RGDfK(azide)]
Research Areas:  

Others

Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] (Cyclo[RGDfK(Azide)]) is a derivative of Cyclo (-RGDfK) (HY-P0023). Cyclo[Arg-Gly-Asp-D-Phe-Lys (Azide)] is a click chemistry reagent containing an azide group. Cyclo[Arg-Gly-Asp-D-Phe-Lys (Azide)] enables functionalization of alginate via SPAAC bioconjugation. Alginate hydrogels functionalized with Cyclo[Arg-Gly-Asp-D-Phe-Lys (Azide)] significantly promote cell expansion while maintaining cell pluripotency .
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Cat. No.: HY-P10392AF
Target:  

Wnt β-catenin

Research Areas:  

Cancer

fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research .
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Cat. No.: HY-W1123941C
Synonyms: Dopamine-PEG2000-azide
Dopamine-PEG2000-N3 (Dopamine-PEG2000-Azide) is a compound composed of dopamine, PEG segments and an azide group (-N3). Dopamine-PEG2000-N3 can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials. Dopamine-PEG2000-N3 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group.
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Cat. No.: HY-W250928C
CAS No.: 956494-20-5
Target:  

Fluorescent Dye

Research Areas:  

Others

Biotin-PEG2000-azide is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; azide, is a moderately good leaving group, can react with alkyne by Cu-catalyzation, which improve the efficiency of biotin binding targets. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Cat. No.: HY-W591449
Target:  

Liposome

Research Areas:  

Cancer

DOPE-PEG2000-Azide is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
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Cat. No.: HY-169232
Target:  

PROTACs PD-1/PD-L1

Research Areas:  

Cancer

PCC16 chloride is a dual PROTAC degrader targeting DHHC3 and PD-L1, with a DC50 of 0.103 μM for PD-L1 degradation. PCC16 chloride induces DHHC3 degradation via the ubiquitin-proteasome pathway by recruiting the CRBN E3 ubiquitin ligase (E3 ubiquitin ligase). By targeting DHHC3-which is essential for PD-L1 palmitoylation and membrane stability-PCC16 chloride reduces PD-L1 levels, decreases PD-L1 membrane retention time, and impairs its immunosuppressive function. PCC16 chloride enhances anti-tumor immunity by disrupting PD-L1-mediated immunosuppression. PCC16 chloride can be used in the research of immune checkpoint blockade-resistant cancers .
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Cat. No.: HY-173606
CAS No.: 1938081-40-3
Research Areas:  

Others

DSPE-PEG2000-Azide ammonium is an azide-functionalized phospholipid and lipid-polyethylene glycol conjugate. DSPE-PEG2000-Azide ammonium serves as a component of azide-functionalized liposome nanoparticles, which enables conjugation with DBCO-modified antibodies and proteins via strain-promoted alkyne-azide cycloaddition, and can also passively insert into exosome membranes through hydrophobic interactions, thereby achieving modular surface engineering via azide-alkyne click chemistry. DSPE-PEG-Azide ammonium binds to bovine milk exosomes with a KD of 347 μM .
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Cat. No.: HY-140682
Research Areas:  

Cancer

m-PEG2000-azide is a PEG derivative. It is a click chemistry reagent. Containing the Azide group, it can undergo a copper-catalyzed azido-azynylene cycloaddition reaction (CuAAc) with molecules containing the Alkyne group. It can also undergo a ring-strain-driven alkyne-azido cycloaddition reaction (SPAAC) with molecules containing the DBCO or BCN groups.
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Cat. No.: HY-174970C
Synonyms: Silane-PEG2000-azide
Silane-PEG2000-N3 (Silane-PEG2000-azide) is a PEG derivative composed of silane, PEG units, and azide groups, which can be used to modify glass, silicon, or other surfaces by reacting hydroxyl groups with ethoxy (methoxy) silanes. Silane-PEG2000-N3 contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
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Cat. No.: HY-182836A
Synonyms: DMPE-PEG2000-azide
DMPE-PEG2000-N3 (DMPE-PEG2000-Azide) is a conjugate composed of DMPE, PEG chains, and terminal azido groups (-N3). DMPE-PEG2000-Azide is a click chemistry reagent used for the targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-W1052051
Synonyms: DPPE-PEG2000-azide
Target:  

Liposome

Research Areas:  

Others

DPPE-PEG2000-N3 (DPPE-PEG2000-Azide) is a conjugate composed of DPPE, PEG chains, and terminal azido groups (-N3). DPPE-PEG2000-Azide is a click chemistry reagent used for the targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-183175A
CAS No.: 3101670-37-2
Target:  

Liposome

Research Areas:  

Others

DSG-PEG2000-N3 is a conjugate composed of DSG, PEG chains, and terminal azido groups (-N3). DSG-PEG2000-Azide is a click chemistry reagent used for the targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-183161A
Synonyms: Glucose-PEG2000-azide
Glucose-PEG2000-N3 (Glucose-PEG2000-Azide) is a conjugate composed of glucose, PEG chains, and an azide group (-N3). Glucose-PEG2000-N3 combines the targeted recognition ability of glucose with the azide group that can undergo click chemistry, making it suitable for applications such as constructing targeted drug delivery systems and nanoparticle modification.
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Cat. No.: HY-P12133
CAS No.: 3080063-21-1
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

Tapimtrutide is a gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. Tapimtrutide can be used for the research of diabetes .
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Cat. No.: HY-P11625
Target:  

RXFP Receptor

Research Areas:  

Cardiovascular Disease

R9-13 is a fatty acid-conjugated relaxin and an agonist of LGR7 (RXFP1). R9-13 induces sustained pubic symphysis elongation in estrogen-pretreated mice. R9-13 exhibits long-acting pharmacokinetic profiles in rodents, with in vivo activity lasting up to one week after administration. R9-13 can be used in studies related to acute heart failure .
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Cat. No.: HY-P11830
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

UDA-6 is a potent calcitonin and amylin receptor agonist (DACRA). UDA-6 induces weight loss, improves metabolic and hepatic parameters, and stabilizes active receptor states in obesity rats. UDA-6 can be used for the research of obesity .
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Cat. No.: HY-P11596
CAS No.: 3107808-75-0
Target:  

Integrin

Research Areas:  

Cancer

NOTA-Asp2-αvβ6L is an integrin αvβ6 binder with selective accumulation in αvβ6-positive pancreatic cancer cells and tumors. NOTA-Asp2-αvβ6L can be used as a PET/CT tracer for imaging pancreatic ductal adenocarcinoma (PDAC) .
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