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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
B0AT1
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "B0AT1" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-B1274
CAS No.: 58473-74-8
Synonyms: trans-3-Bromo-N-ethylcinnamamide
Target:
Research Areas:
Cinromide is an anticonvulsant agent. Cinromide inhibits epithelial neutral amino acid transporter B 0AT1 (SLC6A19) with an IC50 of 0.5 μM .
Cat. No.: HY-162864
CAS No.: 1021125-90-5
Target:
Research Areas:
JX237 is an inhibitor of the epithelial neutral amino acid transporter B 0AT1 (SLC6A19) with an IC50 value of 31 nM. SLC6A19 is the main transporter for the absorption of neutral amino acids in the intestines and their reabsorption in the kidneys. By inhibiting B 0AT1, JX237 can be used for the study of disorders of amino acid metabolism .
Cat. No.: HY-187959
CAS No.: 851269-95-9
Target:
Research Areas:
SLC6A19-IN-6 is a B0AT1 (SLC6A19) inhibitor. SLC6A19-IN-6 inhibits sodium-dependent neutral amino acid transport. SLC6A19-IN-6 can be used for research on non-alcoholic steatohepatitis .
Cat. No.: HY-RS13305
Target:
Research Areas:
SLC6A19 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC6A19 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-179581
CAS No.: 2962069-39-0
Target:
Research Areas:
SLC6A19-IN-4 is an allosteric-competitive and orally active B 0AT1 inhibitor. SLC6A19-IN-4 inhibits both human and mouse B 0AT1 with IC50 values of 513 nM and 295 nM, respectively. SLC6A19-IN-4 exhibits excellent metabolic stability. SLC6A19-IN-4 significantly increases urinary phenylalanine (Phe) excretion and reduces plasma Phe levels through dual inhibition of B 0AT1 in both the intestine (reducing absorption) and kidney (promoting excretion) in vivo. SLC6A19-IN-4 can be used for phenylketonuria (PKU) and other disorders involving SLC6-family transporters research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
