1 Result for "

BIBN99

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BIBN99" in MCE Product Catalog:

Cat. No.: HY-119953
CAS No.: 145301-48-0
Target:  

mAChR

Research Areas:  

Neurological Disease

BIBN-99 is a lipophilic M2 muscarinic receptor antagonist that crosses the blood-brain barrier (human pKi = 7.52; rat pKi = 7.57). BIBN-99 enhances acetylcholine release by blocking presynaptic M2 autoreceptors and heteroreceptors, and reverses impaired acetylcholine release. BIBN-99 can be used in research on dementia, age-related cognitive decline, Alzheimer's disease, and traumatic brain injury .
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