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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
BMX001
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "BMX001" in MCE Product Catalog:
Cat. No.: HY-125662A
CAS No.: 1379783-91-1
Research Areas:
BMX-001 is a blood-brain barrier-penetrant, redox-active manganese porphyrin SOD mimetic with reactive oxygen species/reactive nitrogen species scavenging activity. BMX-001 inhibits NF-κB through S-glutathionylation, activates Nrf2/Keap1, and decreases TRPV1. BMX-001 enhances glucose-stimulated insulin secretion and inhibits islet apoptosis. BMX-001 radiosensitizes tumors, reduces cancer-associated fibroblasts, promotes dendritic cell maturation, modulates macrophage/MDSC/T cell responses, inhibits EMT/angiogenesis/hypoxia/inflammation, and induces apoptosis. BMX-001 protects glial cells while exerting pro-oxidant effects in cancer, and alleviates neuropathic pain. BMX-001 has neuroprotective effects in ischemic stroke. BMX-001 can be used for research on type 1 diabetes, ischemic stroke, pain, breast cancer, and glioblastoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
