437 Results for "

BSA binder

" in MedChemExpress (MCE) Product Catalog:
Products (437)

437 Results for "BSA binder" in MCE Product Catalog:

69
69 Publications Verification
Cat. No.: HY-D0842
CAS No.: 9048-46-8
Synonyms: Albumin bovine serum; BSA
BSA Protein (Bovine Serum Albumin; BSA) is a 583-residue protein consisting of three homologous all-α domains, organized in a heart-shaped structure. BSA is a globular protein that is used in numerous biochemical applications.
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11
11 Cited Publications
Cat. No.: HY-16293
CAS No.: 497871-47-3
Synonyms: PM01183; LY-01017
Research Areas:  

Cancer

Lurbinectedin (PM01183) is a DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC50 values of 1.25 and 1.16 nM, respectively.
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8
8 Cited Publications
Cat. No.: HY-133821
CAS No.: 142234-85-3
Purity:  97.83%
N-Methylmesoporphyrin IX (NMM), a widely used G-quadruplex DNA specific fluorescent binder, is an efficient probe for monitoring Aβ fibrillation. N-Methylmesoporphyrin IX is an in situ inhibitor and an ex situ monitor for Aβ amyloidogenesis both in vitro and in cells. N-Methylmesoporphyrin IX is sensitive to G-quadruplexes DNA but has no response to duplexes, triplexes and single-stranded forms DNA. N-Methylmesoporphyrin IX is nonfluorescent alone or in monomeric Aβ environments, but emits strong fluorescence through stacking with the Aβ assemblies .
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7
7 Cited Publications
Cat. No.: HY-N1428C
CAS No.: 3522-50-7
Synonyms: Iron(III) citrate; Zerenex
Ferric citrate (Iron(III) citrate), an orally active iron supplement, is an efficacious phosphate binder. Ferric citratee can be used for iron deficiency anemia and chronic kidney disease (CKD) research .
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6
6 Cited Publications
Cat. No.: HY-141539A
Purity:  99.77%
Research Areas:  

Cancer

SETDB1-TTD-IN-1 TFA is a potent, selective and endogenous binder competitive ligand of SET domain bifurcated protein 1 tandem tudor domain (SETDB1-TTD) that binds to TTD, with a Kd of 88 nM. SETDB1-TTD-IN-1 TFA increases SETDB1 methyltransferase activity. SETDB1-TTD-IN-1 TFA can be used for the research of biological functions and disease associations of SETDB1-TTD .
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5
5 Cited Publications
Cat. No.: HY-D2449
DQ-BSA-Red is a bovine serum albumin labeled with a red fluorescent dye that can be used to detect lysosomal activity. The excitation wavelength and emission wavelength of DQ-BSA-Red are 590 nm and 620 nm, respectively. The BSA molecule in DQ-BSA-Red is labeled with high concentration of red fluorescent dye in multiple sites, which shows high fluorescence self-inhibition. Once DQ-BSA-RED enters the lysosome, DQ-BSA is cleaved by lysosomal proteases, resulting in unquenched and released fluorescent fragments, emitting bright fluorescence. Inactivated lysosomes are unable to degrade the BSA protein and thus have a lower or even no fluorescent signal .
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4
4 Cited Publications
Cat. No.: HY-106254
CAS No.: 439085-51-5
Synonyms: BTA798
Target:  

Enterovirus

Research Areas:  

Infection

Vapendavir (BTA798) is a potent enteroviral capsid binder (CB). Vapendavir (BTA798) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains .
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4
4 Cited Publications
Cat. No.: HY-106254A
CAS No.: 1198151-75-5
Purity:  98.75%
Synonyms: BTA798 diphosphate
Target:  

Enterovirus

Research Areas:  

Infection Inflammation/Immunology

Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains .
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3
3 Cited Publications
Cat. No.: HY-B0327A
CAS No.: 84504-69-8
Synonyms: Dicloguamine maleate; MN1695
Research Areas:  

Inflammation/Immunology

Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder.
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3
3 Cited Publications
Cat. No.: HY-P2288A
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

WL47 TFA, a high-affinity cavolin-1 (CAV1) ligand (Kd=23 nM), is a potent disrupter of CAV1 oligomers. WL47 TFA shows selectivity for CAV1 over BSA, casein and HEWL. WL47 TFA is 80% smaller in length than the original T20 (HY-P0052) parent sequence and can be used for the study of caveolin-1 function .
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2
2 Cited Publications
Cat. No.: HY-D0842A
CAS No.: 9048-46-8
Synonyms: Bovine Serum Albumin (Low Endotoxin,Fatty acid free)
BSA Protein (Low Endotoxin,Fatty acid free) (Bovine Serum Albumin (Low Endotoxin,Fatty acid free)) is a 583 amino acid globular protein and oligonucleotide binding protein composed of three homologous full α domains. BSA Protein (Low Endotoxin,Fatty acid free) blocks the overall binding of oligonucleotides to cells. BSA Protein (Low Endotoxin,Fatty acid free) regulates the development of hamster embryos and induces arthritis .
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2
2 Cited Publications
Cat. No.: HY-D0859
CAS No.: 1132-61-2
Research Areas:  

Others

MOPS is a buffering agent used in biology. MOPS buffer maintains the pH of mammalian cell culture media. MOPS significantly improves the thermal stability of BSA (HY-D0842) .
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2
2 Cited Publications
Cat. No.: HY-D0859A
CAS No.: 71119-22-7
MOPS sodium salt is a buffering agent used in biology. MOPS buffer maintains the pH of mammalian cell culture media. MOPS sodium salt significantly improves the thermal stability of BSA (HY-D0842) .
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2
2 Cited Publications
Cat. No.: HY-153713
Purity:  98.05%
Target:  

RIBOTAC c-Myc Apoptosis

Research Areas:  

Cancer

MYC-RIBOTAC is a nucleic acid-targeting degrader (ribonuclease-targeting chimera, RIBOTAC) that targets the MYC internal ribosome entry site (IRES). MYC-RIBOTAC contains a MYC mRNA binding component and a small molecule that recruits and locally activates RNAse L1. MYC-RIBOTAC reduces MYC mRNA and protein expression levels, induces cell apoptosis, and can be used for antitumor research . MYC-RIBOTAC consists of pre-miR-155 binder Anticancer agent 167 (HY-156839), RNA binder NCI-B16 (HY-156215), and Linker Amino-PEG4-alcohol (HY-W008005).
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2
2 Cited Publications
Cat. No.: HY-132296
CAS No.: 2743427-26-9
Purity:  99.26%
Target:  

FAK PROTACs

Research Areas:  

Cancer

GSK215 is a potent and selective PROTAC focal adhesion kinase (FAK) degrader with a pDC50 of 8.4. GSK215 is designed by a binder for the VHL E3 ligase and the FAK inhibitor VS-4718. GSK215 induces rapid and prolonged FAK degradation, giving a long-lasting effect on FAK levels and a marked pharmacokinetic/pharmacodynamics (PK/PD) disconnect .
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2
2 Cited Publications
Cat. No.: HY-119323
CAS No.: 95633-27-5
Purity:  99.11%
Target:  

Fluorescent Dye

Research Areas:  

Others

7-Azido-4-methylcoumarin is a selective coumarin-based fluorescent probe for hydrogen sulfide (H2S). In the presence of H2S, the aromatic azido group of 7-Azido-4-methylcoumarin is selectively reduced to produce the fluorescently active 7-amino-4-methylcoumarin (AMC). 7-Azido-4-methylcoumarin binds to the coumarin/phenol-binding site of BSA, the aglycone-binding site of UGT1A6, and the substrate-binding site of SULT1A1, respectively. 7-Azido-4-methylcoumarin retains its fluorescent properties after covalent binding, acts as a fluorescent H2S probe, and does not react with cysteine, homocysteine or glutathione (Ex/Em = 340/445 nm) .
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1
1 Cited Publications
Cat. No.: HY-NP181
Testosterone/BSA, a conjugate of Testosterone (HY-113415) and bovine serum albumin (BSA), acts as a nuclear transporter and cytoplasmic accumulator. Testosterone/BSA can enter the nuclei of rat testicular spermatocytes, spermatids and rat liver endothelial cells, while the antigenicity of BSA remains intact. Testosterone/BSA accumulates in the cytoplasm of rat hepatocytes in granular form. Testosterone/BSA can be used to investigate the membrane-initiated or non-genomic activities of steroid hormones .
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1
1 Cited Publications
Cat. No.: HY-NP001
Synonyms: Cationic Bovine Serum Albumin
Cationic BSA Protein (Cationic Bovine Serum Albumin) is a bovine serum albumin (BSA) modified with excess ethylenediamine, which has enhanced immunogenicity compared to native BSA. Positively charged primary amines block all negatively charged carboxyl groups, making Cationic BSA Protein a cationic protein. Cationic BSA Protein has remarkable neuroprotective effects on ischemic stroke when in combination with Tanshinone IIA (HY-N0135) .
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1
1 Cited Publications
Cat. No.: HY-158285
Purity:  ≥95.0%
25-OH Vitamin D3/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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1
1 Cited Publications
Cat. No.: HY-161541
Estradiol/BSA is the antigen-adjuvant conjugate formed by the coupling of Estradiol (HY-B0141) with Bovine Serum Albumin (BSA). By coupling the antigen with a protein adjuvant, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or disrupt major epitopes, and it can enhance cross-presentation and the generation of antigen-specific T cells.
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