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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
67 Results for "
C. elegans
" in MedChemExpress (MCE) Product Catalog:
Products (67)
67 Results for "C. elegans" in MCE Product Catalog:
10
Category:
Cardiovascular Disease Anti-aging Pyridine Alkaloids Solanaceae Extract Alkaloids Solanum lycopersicum L. Extract Plant Disease Research Fields Inflammation/Immunology Steroids
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10
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Cardiovascular Disease Solanum lycopersicum L. Extract Plant Disease Research Fields Solanaceae Extract Steroids
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5
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3
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2
2 Cited Publications
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5-Ph-IAA-AM is an eggshell-permeable 5-Ph-IAA (HY-134653) analog which contains an acetoxymethyl (AM) group. 5-Ph-IAA-AM affords an enhanced protein degradation in laid embryos. 5-Ph-IAA-AM can be used to disclosure the roles of proteins in C. elegans, in particular those that are involved in embryogenesis and development, through temporally controlled protein degradation .
1
1 Cited Publications
Cat. No.: HY-W035409
CAS No.: 1001625-82-6
RPW-24 protects C. elegans from bacterial infection by stimulating the host immune response of the nematode. RPW-24 has antibacterial activity .
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1 Cited Publications
Cat. No.: HY-W728085
CAS No.: 68054-78-4
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CPPD-Q is a PPD-quinone. CPPD-Q induces increased intestinal permeability and oxidative stress in C. elegans. CPPD-Q targets HMP-2 and ACS-22 to regulate the intestinal barrier, and targets SOD-3 and GST-4 to mediate oxidative stress responses. CPPD-Q induces reactive oxygen species (ROS) production through quinone-mediated redox cycling, and exhibits oxidative potential through dithiothreitol depletion. CPPD-Q is used in research related to intestinal diseases .
Cat. No.: HY-W015924
CAS No.: 594-61-6
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Cat. No.: HY-N0059
CAS No.: 10323-20-3
Synonyms: N-Behenoyl-D-erythro-sphingosine; C22-Ceramide; Cer d18:1/22:0
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C22-Ceramide (d18:1/22:0) (N-Behenoyl-D-erythro-sphingosine) is an ultra-long-chain ceramide containing a C22:0 behenoyl acyl chain. C22-Ceramide can be glycosylated via CGT-3 to form C22 glucosylceramide (C22 GlcCer), which in turn maintains clathrin membrane localization and lysosomal homeostasis, inhibits TOR signaling and promotes SKN-1 activation, thereby enhancing oxidative stress resistance and extending the lifespan of C. elegans. C22-Ceramide can be used in research on cardiometabolic diseases such as type 2 diabetes, obesity, dyslipidemia, coronary artery disease and thin-cap fibroatheroma (TCFA), as well as oxidative stress and aging-related studies .
Cat. No.: HY-170794
CAS No.: 2035010-37-6
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ALT-007 is an orally active serine palmitoyltransferase (SPT) inhibitor that selectively reduces the levels of toxic very-long-chain deoxysphingolipids to enhance protein homeostasis. ALT-007 restores aging-related loss of muscle mass in a mouse model of sarcopenia. ALT-007 enhances protein homeostasis in both mouse and C. elegans models of aging and disease. ALT-007 can be used for age-related neuromuscular diseases research .
Cat. No.: HY-N7082
CAS No.: 28697-53-2
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Microsomal aminopeptidase, Microorganism is first reported from C. elegans. The Microsomal aminopeptidase, Microorganism is beneficial for the development of molecular vaccines against parasitic nematodes .
Cat. No.: HY-N6974
CAS No.: 946524-24-9
Synonyms: Ascaroside C6
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Synonyms: 5-(4-Phenylbutoxy)psoralen
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Psora-4 (5-(4-Phenylbutoxy) psoralen) is a selective Kv1.3 blocker (Kd = 3 nM). Psora-4 increases mitochondrial ROS production, activates stress response genes including daf-16 targets and heat shock proteins, reduces triglyceride accumulation, extends lifespan and healthspan in C. elegans, and increases resistance to Paraquat-induced oxidative stress. Psora-4 can be used for research on psoriasis and obesity .
Cat. No.: HY-125731R
CAS No.: 360-65-6
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Cat. No.: HY-W015924R
CAS No.: 594-61-6
Cat. No.: HY-N7082R
CAS No.: 28697-53-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
