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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
C126
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "C126" in MCE Product Catalog:
Cat. No.: HY-161242A
Target:
Research Areas:
CBI1 formic is a covalent BAX inhibitor. CBI1 formic selectively derivatizes BAX at C126 and inhibits BAX activation by triggering ligands or point mutagenesis. CBI1 formic blocks t-2-hex lipidation and oligomerization of BAX. CBI1 formic inhibits BAX activation induced by BH3 ligands, F116A mutagenesis or t-2-hex .
Cat. No.: HY-161242
Target:
Research Areas:
CBI1 is a covalent BAX inhibitor. CBI1 selectively derivatizes BAX at C126 and inhibits BAX activation by triggering ligands or point mutagenesis. CBI1 blocks t-2-hex lipidation and oligomerization of BAX. CBI1 inhibits BAX activation induced by BH3 ligands, F116A mutagenesis or t-2-hex .
Cat. No.: HY-189689
CAS No.: 3020765-79-8
Target:
Research Areas:
WX-02-16 is a BAX inhibitor. WX-02-16 covalently and stereoselectively modifies BAX C126, restricting BAX conformational dynamics and blocking BAX activation and mitochondrial cytochrome c release. WX-02-16 protects Bak-deficient cells from apoptosis (apoptosis). WX-02-16 protects primary sensory neurons from apoptosis, improving survival and reducing caspase-3/7 activity. WX-02-16 can be used in research on various diseases and injuries triggered by BAX-dependent cell death .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
