2 Results for "

CD81 receptor

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "CD81 receptor" in MCE Product Catalog:

Cat. No.: HY-P991200

Target:  

HCV Claudin

Research Areas:  

Infection

OM-7D3-B3 is an antibody-based antiviral agent targeting the tight junction protein CLDN1 (Kd=4 nM). By binding to the first extracellular domain of CLDN1, OM-7D3-B3 disrupts the formation of the CLDN1-CD81 co-receptor complex, thereby effectively inhibiting the entry of hepatitis C virus (HCV). OM-7D3-B3 not only prevents de novo and chronic HCV infections in humanized liver chimeric mice and uPA-SCID mice transplanted with human livers, but also exhibits favorable safety with no toxic effects observed. OM-7D3-B3 serves as a critical tool for research on HCV infection mechanisms and antiviral drug development .
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Cat. No.: HY-N1036
CAS No.: 508-04-3
Synonyms: (-)-δ-Amyrin; δ-Amyrenol
Research Areas:  

Infection Metabolic Disease

δ-Amyrin ((-)-δ-Amyrin; δ-Amyrenol) is a pentacyclic triterpenoid that is isolated from the bark of Scaevola floribunda. δ-Amyrin is a CD81 receptor binding agent that occupies the active site of CD81 to impede HCV E2-mediated viral entry. δ-Amyrin also exhibits hepatoprotective activity. δ-Amyrin is used in research on hepatitis C virus infection and liver injury .
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