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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
54 Results for "
CMK
" in MedChemExpress (MCE) Product Catalog:
Products (54)
54 Results for "CMK" in MCE Product Catalog:
10
10 Cited Publications
Cat. No.: HY-52101
CAS No.: 821794-90-5
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CMK is a RSK2 kinase inhibitor which exhibits similar potency but less chemical stability compared with FMK.
39
39 Publications Verification
Cat. No.: HY-16990
CAS No.: 178603-78-6
Synonyms: Caspase-1 Inhibitor II
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Ac-YVAD-cmk (Caspase-1 Inhibitor II) is a selective caspase-1 (IL-1beta converting enzyme, ICE)) inhibitor with neuroprotective and anti-inflammatory effects. Ac-YVAD-cmk effectively suppresses the expression of IL-1β and IL-18. Ac-YVAD-cmk inhibits pyroptosis in many diseases .
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13 Cited Publications
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Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1 (IC50 of 46.7 nM), caspases-4 (IC50 of 1.49 μM), caspases-5 (IC50 of 329 nM), and caspases-11 , but not the apoptotic caspases such as caspase-3 .
3
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3
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2
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2
2 Cited Publications
Cat. No.: HY-P3434A
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2
2 Cited Publications
Cat. No.: HY-P70008
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL9; Monokine Induced By Interferon-Gamma; Prev. CMK; Chemokine (C-X-C Motif) Ligand 9; Prev. MIG; Small-Inducible Cytokine B9; SCYB9; C-X-C Motif Chemokine 9; Crg-10; Alternative Protein CXCL9; Humig; HuMIG; Monokine Induced By Gamma Interferon; C-X-C
Species:
Mouse
Source:
HEK293
1
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Decanoyl-RVKR-CMK (DecRVKRcmk) inhibits over-expressed gp160 processing and HIV-1 replication .
1
1 Cited Publications
Synonyms: DecRVKRCMK TFA
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1
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Caspase-9 Inhibitor III (Ac-LEHD-cmk) is a caspase-9 inhibitor. Caspase-9 Inhibitor III exhibits protective effects on ischemia-reperfusion-induced myocardial injury .
1
1 Cited Publications
Cat. No.: HY-P7253
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL9; Monokine Induced By Interferon-Gamma; Prev. CMK; Chemokine (C-X-C Motif) Ligand 9; Prev. MIG; Small-Inducible Cytokine B9; SCYB9; C-X-C Motif Chemokine 9; Crg-10; Alternative Protein CXCL9; Humig; HuMIG; Monokine Induced By Gamma Interferon; C-X-C
Species:
Human
Source:
E. coli
Cat. No.: HY-P4284
CAS No.: 35172-59-9
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Synonyms: Elastase Inhibitor III
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MeOSuc-AAPV-CMK (Elastase Inhibitor III) is an elastase inhibitor that simultaneously inhibits Cathepsin G and Proteinase 3. MeOSuc-AAPV-CMK blocks the shedding of FcgRIIIb on the surface of human neutrophils. MeOSuc-AAPV-CMK reverses the elastase-mediated reduction in proinflammatory cytokine production by immune cells, partially restores IL-1β levels in immune cell co-culture systems, and prevents elastase-mediated adiponectin cleavage .
Cat. No.: HY-P10939A
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Cat. No.: HY-W796158
CAS No.: 250584-13-5
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Cat. No.: HY-P10939
CAS No.: 2588354-33-8
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Cat. No.: HY-P5994
CAS No.: 137259-05-3
Synonyms: MeOSuc-Ala-Ala-Pro-Phe-CH₂Cl
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Cat. No.: HY-P5062A
Synonyms: Decanoyl-Arg-Val-Arg-Lys-chloromethylketone TFA
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DEC-RVRK-CMK TFA (Decanoyl-Arg-Val-Arg-Lys-chloromethylketone TFA) is a peptidyl CMK inhibitor that targets the calcium-dependent subtilisin-like proprotein convertase family. DEC-RVRK-CMK TFA is a furin-targeting proprotein convertase inhibitor that blocks the cleavage and maturation of inhibin α-subunit and βB-subunit precursors. DEC-RVRK-CMK TFA inhibits PC4-mediated proteolysis with an IC50 of 12.2 nM in rats. DEC-RVRK-CMK TFA holds promise for antiviral infection-related research .
Cat. No.: HY-P5062
CAS No.: 534615-50-4
Synonyms: Decanoyl-Arg-Val-Arg-Lys-chloromethylketone
Target:
Research Areas:
DEC-RVRK-CMK (Decanoyl-Arg-Val-Arg-Lys-chloromethylketone) is a peptidyl CMK inhibitor that targets the calcium-dependent subtilisin-like proprotein convertase family. DEC-RVRK-CMK is a furin-targeting proprotein convertase inhibitor that blocks the cleavage and maturation of inhibin α-subunit and βB-subunit precursors. DEC-RVRK-CMK inhibits PC4-mediated proteolysis with an IC50 of 12.2 nM in rats. DEC-RVRK-CMK holds promise for antiviral infection-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
