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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
CPT I
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "CPT I" in MCE Product Catalog:
75
75 Publications Verification
Synonyms: Campathecin; (S)-(+)-Camptothecin; CPT
1
1 Cited Publications
Synonyms: 9-Amino-20(S)-camptothecin; 9-Amino-CPT
Category:
Nyssaceae Extract Alkaloids Plant Camptotheca acuminata Decne. Extract Disease Research Fields Cancer Indole Alkaloids
Target:
1
1 Cited Publications
Cat. No.: HY-U00159
CAS No.: 69207-52-9
Synonyms: Methyl palmoxirate; NSC359682
Research Areas:
McN3716 is a carnitine palmitoyltransferase I (CPT-1) inhibitor.
Target:
Research Areas:
Deruxtecan analog 2 (example 9 P3) is a Deruxtecan (HY-13631E) analog. Deruxtecan analog 2 is a agent-linker conjugate composed of Camptothecin (HY-16560) and a linker. Camptothecin (CPT) is a Topo I inhibitor with antineoplastic activity against colorectal, breast, lung and ovarian cancers. Deruxtecan analog 2 can be used for the preparation anti-FGFR2 ADC .
Synonyms: APC
Target:
Research Areas:
RPR121056 (APC) is a metabolite of Irinotecan (CPT-11), which is generated by CYP3A4. Irinotecan (CPT-11) is an antineoplastic agent that inhibits topoisomerase type I, causing cell death, and is widely used in the treatment of colorectal cancer. Irinotecan also directly inhibits AChE .
Cat. No.: HY-W104819
CAS No.: 15573-67-8
Synonyms: 4-Hydroxyphenylglyoxylic acid; 4-HPGA
Research Areas:
4-Hydroxyphenylglyoxylate (4-Hydroxyphenylglyoxylic acid) is an inhibitor of carnitine palmitoyltransferase I (CPT I). 4-Hydroxyphenylglyoxylate can be used to study sensitivity changes in CPT I of liver mitochondria and fatty acid oxidation by isolated hepatocytes. 4-Hydroxyphenylglyoxylate can inhibits fatty acid oxidation .
Cat. No.: HY-16560S
CAS No.: 1329616-37-6
Synonyms: Campathecin-d5; (S)-(+)-Camptothecin-d5; CPT-d5
Cat. No.: HY-120994B
CAS No.: 129693-13-6
Target:
Research Areas:
Sp-8-CPT-cAMPS, a cAMP analog, is a potent and selective activator of the cAMP-dependent protein kinas A (PKA I and PKA II). Sp-8-CPT-cAMPS selects site A of RI compares to site A of RII by 153-fold and site B of RII compares to site B of RI by 59-fold .
Cat. No.: HY-113510
CAS No.: 89886-42-0
Cat. No.: HY-172548
Research Areas:
Docosahexaenoyl-L-carnitine chloride is a long-chain acylcarnitine composed of Docosahexaenoic acid (HY-B2167) and L-carnitine (HY-B0399). Docosahexaenoyl-L-carnitine chloride is transported into mitochondria for β -oxidation and decomposition under the action of carnitine palmitoyltransferase I (CPT I) and others. Docosahexaenoyl-L-carnitine chloride is promising for research of diseases related to fatty acid metabolism .
Cat. No.: HY-RS03122
Research Areas:
CPT1A Human Pre-designed siRNA Set A contains three designed siRNAs for CPT1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-120994A
CAS No.: 129735-01-9
Target:
Research Areas:
Rp-8-CPT-cAMPS, a cAMP analog, is a potent and competitive antagonist of cAMP-induced activation of cAMP-dependent PKA I and II. Rp-8-CPT-cAMPS preferentially selects site A of RI compares to site A of RII and site B of RII compares to site B of RI .
Synonyms: Campathecin (Standard); (S)-(+)-Camptothecin (Standard); CPT (Standard)
Cat. No.: HY-145513
CAS No.: 1084888-82-3
Target:
Research Areas:
CL2-MMT-SN38 is a SN-38 derivative. SN-38, an anticancer agent, is an active metabolite of the Topoisomerase I inhibitor Irinotecan (CPT-11) .
Cat. No.: HY-100620R
CAS No.: 181467-56-1
Synonyms: APC (Standard)
Research Areas:
RPR121056 (Standard) is the analytical standard of RPR121056. This product is intended for research and analytical applications. RPR121056 (APC) is a metabolite of Irinotecan (CPT-11), which is generated by CYP3A4. Irinotecan (CPT-11) is an antineoplastic agent that inhibits topoisomerase type I, causing cell death, and is widely used in the treatment of colorectal cancer. Irinotecan also directly inhibits AChE[1].
Cat. No.: HY-120638
CAS No.: 406913-72-2
Target:
Research Areas:
BMS-250749 is a topoisomerase I (Top I) inhibitor of the fluoroglycosyl-3,9-difluoroindolecarbazole class. BMS-250749 exhibits potent cytotoxicity and selectivity, and shows curative antitumor activity against Lewis lung cancer. BMS-250749 exhibits broad-spectrum antitumor activity superior to CPT-11 in certain preclinical xenograft models. .
Cat. No.: HY-120994
CAS No.: 221905-35-7
Target:
Research Areas:
Rp-8-CPT-cAMPS sodium, a cAMP analog, is a potent and competitive antagonist of cAMP-induced activation of cAMP-dependent PKA I and II. Rp-8-CPT-cAMPS sodium preferentially selects site A of RI compares to site A of RII and site B of RII compares to site B of RI .
Cat. No.: HY-16149
CAS No.: 157244-53-6
Synonyms: CPI-975
Research Areas:
SDZ-CPI-975 is a novel, reversible, and selective CPT I inhibitor. SDZ-CPI-975 effectively inhibits fatty acid oxidation and lowers blood glucose levels .
Cat. No.: HY-132561S
CAS No.: 1217816-76-6
Synonyms: APC-d3
Cat. No.: HY-146094
CAS No.: 1627600-90-1
Target:
Research Areas:
Antitumor agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, is an antitumor agent without toxicity towards normal cells. Antitumor agent-63 shows high stability and very weak direct topoisomerase I (Topo I) inhibition .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
