4

GRO-alpha/CXCL1 Protein, Human (HEK293, His)

4 Cited Publications

Purity: ≥ 95%, as determined by reducing SDS-PAGE.

Synonyms: CXCL1; Neutrophil-Activating Protein 3; Prev. GRO1; Fibroblast Secretory Protein; Prev. MGSA; C-X-C Motif Chemokine 1; Prev. FSP; GRO-Alpha(1-73); SCYB1; GRO1 Oncogene (Melanoma Growth-Stimulating Activity); NAP-3; Melanoma Growth Stimulatory Activity Alpha; MGSA-A; Melanoma Growth Stimulatory Activity; GROa; MGSA Alpha; Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha); GROA; GRO1 Oncogene (Melanoma Growth Stimulating Activity, Alpha); GRO; Melanoma Growth Stimulating Activity, Alpha; C-X-C Motif Chemokine Ligand 1; Growth-Regulated Alpha Protein

Species:

Human

Source:

HEK293

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2

GRO-alpha/CXCL1 Protein, Mouse

2 Cited Publications

Cat. No.: HY-P7188

Purity: ≥ 95%, as determined by reducing SDS-PAGE.

Synonyms: CXCL1; Neutrophil-Activating Protein 3; Prev. GRO1; Fibroblast Secretory Protein; Prev. MGSA; C-X-C Motif Chemokine 1; Prev. FSP; GRO-Alpha(1-73); SCYB1; GRO1 Oncogene (Melanoma Growth-Stimulating Activity); NAP-3; Melanoma Growth Stimulatory Activity Alp

Species:

Mouse

Source:

E. coli

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SX-517

Cat. No.: HY-12927

CAS No.: 1240494-13-6

Purity: 99.88%

Target:

CXCR

Research Areas:

Inflammation/Immunology

SX-517 is a dual CXCR2/1 antagonist, containing boronic acid. SX-517 inhibits CXCL1-induced Ca ²⁺ flux (IC₅₀=38 nM), and antagonizes CXCL8-induced [(35)S]GTPγS binding (IC₅₀=60 nM) and ERK1/2 phosphorylation. SX-517 has significant ability for inflammation suppression, in both humanized polymorphonuclear (PMN) cells and in murine model ^[1] .

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