20

20 Publications Verification

Category:

Anti-aging Disease Research Antibacterial Endogenous metabolite Other Antibiotics Infection Human Gut Microbiota Metabolites Microorganisms Plant Cell Culture Antibiotics Resistance Selection Animal Husbandry Anticancer Disease Research Fields Cancer

Target:

Antibiotic Bacterial HIF/HIF Prolyl-Hydroxylase VEGFR Autophagy Apoptosis Beclin1 JNK Akt MMP

Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

3

Chloramphenicol succinate sodium

3 Cited Publications

Cat. No.: HY-N7114A

CAS No.: 982-57-0

Category:

Infection Microorganisms Antibiotics Metabolic Disease Disease Research Antibacterial Disease Research Fields Other Antibiotics

Target:

Bacterial P2Y Receptor Succinate Dehydrogenase Drug Intermediate

Chloramphenicol succinate sodium is a prodrug of Chloramphenicol (HY-B0239), acting as a P2Y14R inhibitor with an IC₅₀ of 1.585 nM. Chloramphenicol succinate sodium serves as a competitive substrate and inhibitor of succinate dehydrogenase (SDH), which may account for its toxicity. Chloramphenicol succinate sodium exerts a significant inhibitory effect on colitis. Chloramphenicol succinate sodium can be used in research related to myelosuppression, gray baby syndrome, aplastic anemia, bacterial meningitis and inflammatory bowel disease .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

Thiamphenicol

Cat. No.: HY-B0479

CAS No.: 15318-45-3

Synonyms: Thiophenicol; Dextrosulphenidol

Target:

Beta-lactamase Bacterial Antibiotic

Research Areas:

Infection

Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

Chloramphenicol-d5

Cat. No.: HY-B0239S

CAS No.: 202480-68-0

Chloramphenicol-d₅ is the deuterium labeled Chloramphenicol. Chloramphenicol is a broad-spectrum antibiotic against bacterial infections .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

Chloramphenicol palmitate

Cat. No.: HY-B1599

CAS No.: 530-43-8

Target:

Bacterial Antibiotic

Research Areas:

Infection

Chloramphenicol palmitate is an orally active prodrug of Chloramphenicol (HY-B0239), obtained from the esterification reaction between the agent and Palmitic acid (HY-N0830). Chloramphenicol palmitate is rapidly and completely hydrolyzed by intestinal esterase, releasing Chloramphenicol. Chloramphenicol is an orally effective broad-spectrum antibiotic .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

Cyclo(L-Pro-L-Val)

Cat. No.: HY-P1938

CAS No.: 2854-40-2

Category:

Natural Products Microorganisms

Target:

Bacterial

Cyclo(L-Pro-L-Val) is an antimicrobial and anti-inflammatory agent. Cyclo(L-Pro-L-Val) has toxic activity against plant pathogens such as R. fascians LMG 3605, and its potency may be comparable to that of Chloramphenicol (HY-B0239). Cyclo(L-Pro-L-Val) can inhibit the phosphorylation of IKKα, IKKβ, NF-κB, etc., and the activation of iNOS and COX-2, thereby exerting anti-inflammatory activity. Cyclo(L-Pro-L-Val) can be used in the research of biopesticides in the agricultural field, as well as in the research of inflammation-related diseases .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

Eperezolid

Cat. No.: HY-10393

CAS No.: 165800-04-4

Purity: 96.11%

Synonyms: PNU-100592

Target:

Bacterial Antibiotic

Research Areas:

Infection

Eperezolid (PNU-100592) is an orally active protein synthesis inhibitor that targets the bacterial 50S ribosomal subunit. Eperezolid competitively binds to a specific site on the ribosomal 50S subunit (overlapping with the binding sites of chloramphenicol (HY-B0239) and lincomycin (HY-117660)) to inhibit the translation initiation stage and exert antibacterial activity. Eperezolid can induce host cell autophagy to enhance the clearance of intracellular mycobacteria, and its MIC₉₀ for Staphylococcus aureus and Enterococcus is 1-4 μg/mL. Eperezolid is mainly used for antibacterial research on infections with Gram-positive bacteria such as methicillin-resistant (HY-121544) Staphylococci and vancomycin-resistant (HY-B0671) Enterococci, as well as infections with intracellular bacteria such as Mycobacterium tuberculosis .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

4-Nitrobenzaldehyde

Cat. No.: HY-W007577

CAS No.: 555-16-8

4-Nitrobenzaldehyde is a widely used industrial chemical intermediate and also the main photodegradation product of the broad-spectrum antibiotic Chloramphenicol (HY-B0239). 4-Nitrobenzaldehyde has genotoxic and mutagenic effects and poses a certain threat to human health and ecosystems .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

Chloramphenicol (Standard)

Cat. No.: HY-B0239R

CAS No.: 56-75-7

Category:

Disease Research Antibacterial Endogenous metabolite Other Antibiotics Human Gut Microbiota Metabolites Microorganisms Plant Cell Culture Antibiotics Resistance Selection Animal Husbandry Anticancer

Target:

Reference Standards Antibiotic Bacterial HIF/HIF Prolyl-Hydroxylase VEGFR Autophagy Apoptosis Beclin1 JNK Akt MMP

Chloramphenicol (Standard) is the analytical standard of Chloramphenicol. This product is intended for research and analytical applications. Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

4'-Nitroacetophenone

Cat. No.: HY-Y0185

CAS No.: 100-19-6

4'-Nitroacetophenone is a nitroaromatic compound. 4'-Nitroacetophenone is an important organic synthetic intermediate, which can be used for the synthesis of other active compounds such as Chloramphenicol (HY-B0239) .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

Thiamphenicol-d3

Cat. No.: HY-B0479S

CAS No.: 2211914-19-9

Synonyms: Thiophenicol-d₃; Dextrosulphenidol-d₃

Thiamphenicol-d₃ is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

4-Amino-L-phenylalanine

Cat. No.: HY-W016480

CAS No.: 943-80-6

Synonyms: H-Phe(4-NH2)-OH

Category:

Alkaloids Other Alkaloids Metabolic Disease Endogenous metabolite Disease Research Fields

Target:

Carbonic Anhydrase Endogenous Metabolite Parasite

4-Amino-L-phenylalanine (H-Phe(4-NH2)-OH) is a metabolic intermediate and an α-carbonic anhydrase (TcCA) activator with a K_a value of 0.75 μM. 4-Amino-L-phenylalanine acts through active site cavity entrance binding and a proton shuttle mechanism to enhance the catalytic rate of CO₂ hydration. 4-Amino-L-phenylalanine serves as a diamine monomer for bio-based polymer synthesis and is produced in Escherichia coli via the shikimate pathway. 4-Amino-L-phenylalanine constitutes a structural component of haptens used in immunoassay development. 4-Amino-L-phenylalanine is used for the production of Chloramphenicol (HY-B0239) and Pristinamycin I in Streptomyces venezuelae and S. pristinaespiralis, respectively. 4-Amino-L-phenylalanine is used in research related to Trypanosoma cruzi infection .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

Levomecol

Cat. No.: HY-111903

CAS No.: 118573-58-3

Category:

Infection Microorganisms Plant Cell Culture Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics

Target:

Bacterial

Levomecol (Chloramphenicol), made up of Chloramphenicol, Methyluracil, is a broad-spectrum antibiotic that is derived from the bacterium Streptomyces venezuelae. Levomecol (Chloramphenicol)) stops bacterial growth by binding to the bacterial ribosome (blocking peptidyl transferase) and inhibiting protein synthesis .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

Cinnamyl acetate

Cat. No.: HY-N7125

CAS No.: 103-54-8

Category:

Simple Phenylpropanols Other Diseases 500 - Internal Server Error | MedChemExpress

country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Cart

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Oops!

Sorry, Something went wrong on our server.
Our team has been notified and is working to fix the issue.