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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
Cleavable fluorescent probe
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "Cleavable fluorescent probe" in MCE Product Catalog:
18
18 Publications Verification
Cat. No.: HY-D0717
CAS No.: 254109-22-3
Synonyms: Diaminofluorescein-FM diacetate
15
Cat. No.: HY-DY1046
CAS No.: 136832-63-8
Solvent and concentration: DMSO: 10 mM
Cat. No.: HY-D1078
CAS No.: 127770-45-0
Cat. No.: HY-149931
CAS No.: 1458731-58-2
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BMV109 is a quenched probe that becomes fluorescent when cleaved and covalently bound by active cathepsin proteases. BMV109 can be exploited for tumor imaging .
Cat. No.: HY-DY1048
CAS No.: 254109-22-3
Solvent and concentration: DMSO: 2 mM
Cat. No.: HY-150175
CAS No.: 1786411-17-3
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HKSOX-1 is a fluorescent probe for the detection and imaging of superoxide anion radicals (O2 •−) with selectivity. HKSOX-1 reacts with superoxide anion radicals, cleaving the aryl triflate group to generate a free phenol and produce turn-on fluorescence. Derivative variants of HKSOX-1 include HKSOX-1r and HKSOX-1m. HKSOX-1 is applicable to studies related to endogenous superoxide detection .
Cat. No.: HY-D2379
CAS No.: 1629965-68-9
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HMRG is a fluorescent dye, which serves as the fluorescent active product generated by enzyme-activated fluorescent probes targeting proteases and glycosidases. Its detection mechanism relies on the intramolecular spirocyclization equilibrium: HMRG itself exists in an open non-spirocyclic structure under physiological pH, which maintains a conjugated π system and produces strong fluorescence; whereas its probe precursors (such as Leu-HMRG, Ac-GlyPro-HMRG and βGal-HMRG) exist in a closed spirocyclic form and show no fluorescence due to the disruption of the π-conjugated system; when the target enzyme cleaves the substrate fragment linked to the probe precursor, the closed spirocyclic structure converts to the open structure of HMRG, restoring the conjugated system and generating a strong fluorescent signal. Its detection wavelength is Ex/Em = 501/524 nm .
Cat. No.: HY-112526
CAS No.: 1004324-99-5
Cat. No.: HY-155486
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HCy-AAN-Bio is a tumor-targeted hemicyanine (HCy) probe for Fluorescent/photoacoustic (FL/PA) imaging of legumain in vivo. Legumain can specifically cleave HCy-AAN-Bio with the generation of FL/PA signal. HCy-AAN-Bio is a powerful tool for early diagnosis of associated cancer .
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closed-HMRG is an HMRG (HY-D2379) with a closed spiro-ring structure. HMRG is a fluorescent dye, which serves as the fluorescent active product generated by enzyme-activated fluorescent probes targeting proteases and glycosidases. Its detection mechanism relies on the intramolecular spirocyclization equilibrium: HMRG itself exists in an open non-spirocyclic structure under physiological pH, which maintains a conjugated π system and produces strong fluorescence; whereas its probe precursors (such as Leu-HMRG, Ac-GlyPro-HMRG and βGal-HMRG) exist in a closed spirocyclic form and show no fluorescence due to the disruption of the π-conjugated system; when the target enzyme cleaves the substrate fragment linked to the probe precursor, the closed spirocyclic structure converts to the open structure of HMRG, restoring the conjugated system and generating a strong fluorescent signal. Its detection wavelength is Ex/Em = 501/524 nm .
Cat. No.: HY-W411215
CAS No.: 83619-73-2
Cat. No.: HY-D3319
Cat. No.: HY-P11595
CAS No.: 2357123-44-3
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Cat. No.: HY-175163
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TPAPyN is a nitroreductase(NTR)-responsive type I photosensitizer. TPAPyN facilitates the imaging of hypoxic cancer cells and image-guided photodynamic therapy (PDT). TPAPyN does not emit fluorescence in the aqueous environment, but restores when NTR cleaves the nitrofuran quencher with aggregation-induced emission. TPAPyN can be used as a fluorescent probe for specific imaging of hypoxic cancer .
Cat. No.: HY-D3096
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TPh-PyBz-β-gal is a fluorescent probe used for the detection and imaging of β-galactosidase (β-gal) in living cells. The detection mechanism of TPh-PyBz-β-gal relies on β-gal, which cleaves the glycosidic bond linking the AIE-active fluorophore and the D-galactose residue unit of the probe. The emission wavelength of TPh-PyBz-β-gal after activation is 606 nm. TPh-PyBz-β-gal has low cytotoxicity and can be applied to β-gal imaging in living cells .
Cat. No.: HY-D3169
CAS No.: 1476735-95-1
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Cat. No.: HY-D2930
Synonyms: SNAP-SS-SulfoCy5
Cat. No.: HY-D3187
CAS No.: 2484831-02-7
Cat. No.: HY-D2924
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
