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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
58 Results for "
CoA biosynthesis
" in MedChemExpress (MCE) Product Catalog:
Products (58)
58 Results for "CoA biosynthesis" in MCE Product Catalog:
5
Research Areas:
Lactyl-CoA is an acyl-CoA formally condensed from the sulfhydryl group of CoA and the carboxyl group of lactic acid, also known as lactyl-CoA. Lactyl-CoA is essential for the biosynthesis of biodegradable and biocompatible lactic acid-based copolymers .
5
5 Cited Publications
Synonyms: Succinyl-CoA sodium
Category:
Natural Products Neurological Disease Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
2
2 Cited Publications
Synonyms: Palmitoyl CoA lithium
2
2 Cited Publications
Cat. No.: HY-44170
CAS No.: 902614-04-4
Target:
Research Areas:
Pantothenate kinase-IN-2 is a pantothenate kinase inhibitor with IC50 values of 92 nM for PanK2, 70 nM for PanK1β, and 25 nM for PanK3. Pantothenate kinase-IN-2 can bind specifically to the ATP-PanK3 complex and block CoA biosynthesis. Pantothenate kinase-IN-2 can be used for the research of pank-associated neurodegeneration and type 2 diabetes .
2
2 Cited Publications
Synonyms: Heptanedioic acid; 1,5-Pentanedicarboxylic acid; 1,7-Heptanedioic acid
Category:
Immune System Disorder Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
1
1 Cited Publications
Synonyms: Antibiotic MB 530A; Lovastatin diol lactone
Target:
Research Areas:
Monacolin J is an inhibitor of cholesterol biosynthesis, and inhibits the activity of HMG-CoA reductase.
1
Category:
Human Gut Microbiota Metabolites Natural Products Other Diseases Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-W015924
CAS No.: 594-61-6
Target:
Cat. No.: HY-E70009
CAS No.: 61116-22-1
Synonyms: ACO
Target:
Research Areas:
Acyl-CoA oxidase (ACO) is a peroxisomal catalyst. Acyl-CoA oxidase acts as a key rate-limiting enzyme in the process of peroxisomal fatty acid β-oxidation. Acyl-CoA oxidase participates in lipid catabolism and phytohormone biosynthesis pathways .
Cat. No.: HY-N7392A
Synonyms: 3-Oxobutanoyl-coenzyme A sodium hydrate
Target:
Category:
Human Gut Microbiota Metabolites Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
Target:
Research Areas:
TSI-01 is a selective LPCAT2 inhibitor, with IC50 values of 0.47 μM and 3.02 μM against LPCAT2 and LPCAT1, respectively. TSI-01 competitively inhibits acetyl-CoA (acetyl-CoA) targeting the lysophosphatidic acid acetyltransferase activity of LPCAT2, and suppresses PAF biosynthesis in calcium ionophore-stimulated mouse peritoneal macrophages. TSI-01 inhibits the proliferation of endometrial cancer cells and promotes endometrial cancer cell apoptosis (apoptosis). TSI-01 can be used for the research of endometrial cancer and PAF-related inflammatory diseases .
Cat. No.: HY-N11658
CAS No.: 30802-00-7
Synonyms: 4-Coumaroyl-CoA; p-coumaroylcoenzyme A
Target:
Synonyms: Succinyl-coenzyme A; S-(Hydrogen succinyl)coenzyme A
Target:
Target:
Herbicide Environmental Pollutants Acetyl-CoA Carboxylase Apoptosis Reactive Oxygen Species (ROS)
Research Areas:
Clethodim is a potent acetyl-CoA A carboxylase (ACCase) inhibitor and herbicide. Clethodim inhibits ACCase in plants, thereby blocking fatty acid biosynthesis required for cell membrane and secondary metabolite production . Clethodim exhibits developmental toxicity and neurotoxicity in zebrafish embryos and larvae. Clethodim is used in studies on agricultural herbicides and developmental toxicity .
Cat. No.: HY-N6663
CAS No.: 13466-78-9
Synonyms: BSN 2060
Research Areas:
Spiromesifen (BSN 2060) is a broad-spectrum
tetrachloro acid derivative acaricide. Spiromesifen reduces lipid biosynthesis via inhibition of acetyl-CoA carboxylase, and has no cross-resistance to any resistant mite or whitefly
populations .
Target:
Research Areas:
Ethylmalonyl-CoA (Ethylmalonyl coenzyme A) is a metabolic intermediate and biosynthetic precursor associated with crotonyl-CoA carboxylase/reductase. Ethylmalonyl‑CoA is generated via the reductive carboxylation of crotonyl-CoA catalyzed by crotonyl-CoA carboxylase/reductase (CCR); it can be recognized by the PKS acyltransferase AT and participate in the biosynthesis of antibiotic polyketide natural products. Ethylmalonyl-CoA is used in biosynthesis-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
