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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
68 Results for "
Curcuma
" in MedChemExpress (MCE) Product Catalog:
Products (68)
68 Results for "Curcuma" in MCE Product Catalog:
8
8 Publications Verification
Synonyms: (-)-β-Elemene; Levo-β-elemene
Category:
Plant Zingiberaceae Extract Terpenoids Sesquiterpenes Curcuma aromatica Salisb. cv. Wenyujin Extract Disease Research Fields Cancer
Target:
2
1
Category:
Plant Zingiberaceae Extract Ketones, Aldehydes, Acids Curcuma longa Extract Disease Research Fields Inflammation/Immunology
Target:
1
1 Cited Publications
Cat. No.: HY-N3651
CAS No.: 20493-56-5
1
1 Cited Publications
Cat. No.: HY-N4121
CAS No.: 24063-71-6
Target:
Cat. No.: HY-W008226
CAS No.: 480-66-0
Synonyms: 2,4,6-trihydroxyacetophenone; 1-(2,4,6-Trihydroxyphenyl)ethanone
Category:
Zingiberaceae Extract Curcuma comosa Roxb. Extract Metabolic Disease Other Families Extract Infection Plant Ketones, Aldehydes, Acids Phenols Polyphenols Disease Research Fields
Target:
Synonyms: DiMC; CHC 004; Di-O-methylcurcumin
Target:
Androgen Receptor Reactive Oxygen Species (ROS) Apoptosis NF-κB CDK Fatty Acid Synthase (FASN) Acetyl-CoA Carboxylase PI3K Akt AMPK ERK JNK
Research Areas:
Dimethoxycurcumin (DiMC) is a curcuminoid compound found in Curcuma longa. Dimethoxycurcumin is also an orally active thioredoxin reductase inhibitor (IC50 = 5.4 μM) and androgen receptor antagonist. Dimethoxycurcumin inhibits thioredoxin reductase, leading to oxidized thioredoxin accumulation, ROS production, DNA damage, glutathione depletion, mitochondrial membrane potential decrease, ATP depletion, S phase arrest, and apoptosis. Dimethoxycurcumin inhibits NF-κB, NADPH oxidase subunits, ATP synthase subunits, CDK4, cyclin-D1, FASN, ACC, and the IRS2-PI3K-Akt pathway, while activating AMPK, ERK, and JNK. Dimethoxycurcumin can be used for research on cancer, arsenic-induced hepatotoxicity, and tuberculosis .
Category:
Natural Products Plant Zingiberaceae Extract Curcuma longa Extract Disease Research Fields Cancer
Target:
Cat. No.: HY-107324R
CAS No.: 515-13-9
Synonyms: (-)-β-Elemene (Standard); Levo-β-elemene (Standard)
Category:
Plant Zingiberaceae Extract Terpenoids Sesquiterpenes Curcuma aromatica Salisb. cv. Wenyujin Extract
Target:
Cat. No.: HY-N0006A
CAS No.: 24939-17-1
Synonyms: p-Hydroxycinnamoyl-feruloylmethane
Category:
Plant Zingiberaceae Extract Phenols Polyphenols Curcuma longa Extract Disease Research Fields Cancer
Target:
Cat. No.: HY-N0893R
CAS No.: 36062-04-1
Synonyms: HZIV 81-2 (Standard)
Cat. No.: HY-N10881
CAS No.: 142717-57-5
Target:
Target:
Cat. No.: HY-N16650
CAS No.: 2871811-08-2
Target:
Cat. No.: HY-N8047
CAS No.: 79559-61-8
Target:
Cat. No.: HY-N7494S
CAS No.: 121578-13-0
Cat. No.: HY-145670
CAS No.: 32663-51-7
cis,trans-Germacrone is an isomer of Germacrone (HY-N0440) and is present in the stems and leaves of Curcuma wenyujin. Germacrone exhibits a wide range of antitumor, antioxidant, and anti-inflammatory effects. Germacrone inhibits lung cancer cell proliferation and alters Akt/MDM2/p53. Germacrone also induces cell cycle arrest at the G1/S phase. Germacrone is used in lung cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
