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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
DR3
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "DR3" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-P7309
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor Necrosis Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of Apoptosis; APO3L; Tumor Necrosis Factor Ligand 4A; Tumor Necrosis Factor Ligand Superfamily Member 12; HCG1991317, Is
Species:
Human
Source:
CHO
1
1 Cited Publications
Cat. No.: HY-P77264
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor Necrosis Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of Apoptosis; APO3L; Tumor Necrosis Factor Ligand 4A; Tumor Necrosis Factor Ligand Superfamily Member 12; HCG1991317, Is
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P990151
Target:
Research Areas:
Cat. No.: HY-P992225
Target:
Research Areas:
Cat. No.: HY-P78566
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF25; Apoptosis-Mediating Receptor DR3; Prev. TNFRSF12; Protein WSL-1; LARD; Tumor Necrosis Factor Receptor Superfamily Member 25 Deletion Mutant; DDR3; Tumor Necrosis Factor Receptor Superfamily, Member 25; DR3; Death Domain Receptor 3 Soluble Form;
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P77522
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF25; Apoptosis-Mediating Receptor DR3; Prev. TNFRSF12; Protein WSL-1; LARD; Tumor Necrosis Factor Receptor Superfamily Member 25 Deletion Mutant; DDR3; Tumor Necrosis Factor Receptor Superfamily, Member 25; DR3; Death Domain Receptor 3 Soluble Form;
Species:
Human
Source:
HEK293
Cat. No.: HY-P705015
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF25; Apoptosis-Mediating Receptor DR3; Prev. TNFRSF12; Protein WSL-1; LARD; Tumor Necrosis Factor Receptor Superfamily Member 25 Deletion Mutant; DDR3; Tumor Necrosis Factor Receptor Superfamily, Member 25; DR3; Death Domain Receptor 3 Soluble Form;
Species:
Human
Source:
HEK293
Cat. No.: HY-P700707
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF25; Apoptosis-Mediating Receptor DR3; Prev. TNFRSF12; Protein WSL-1; LARD; Tumor Necrosis Factor Receptor Superfamily Member 25 Deletion Mutant; DDR3; Tumor Necrosis Factor Receptor Superfamily, Member 25; DR3; Death Domain Receptor 3 Soluble Form;
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P704568
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF25; Apoptosis-Mediating Receptor DR3; Prev. TNFRSF12; Protein WSL-1; LARD; Tumor Necrosis Factor Receptor Superfamily Member 25 Deletion Mutant; DDR3; Tumor Necrosis Factor Receptor Superfamily, Member 25; DR3; Death Domain Receptor 3 Soluble Form; WSL-LR; Apoptosis Inducing Receptor; TRAMP; Death Receptor Beta; WSL-1; Death Receptor 3; APO-3; Protein WSL; TR3; Apo-3; Tumor Necrosis Factor Receptor Superfamily, Member 12 (Translocating Chain-Association Membrane Protein); APO3; Tumor Necrosis Factor Receptor Superfamily Member 25; WSL1; Lymphocyte-Associated Receptor Of Death; WSL; Apoptosis-Mediating Receptor TRAMP; TNF Receptor Superfamily Member 25; Apoptosis-Inducing Receptor AIR
Species:
Human
Source:
HEK293
Cat. No.: HY-P705014
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF25; Apoptosis-Mediating Receptor DR3; Prev. TNFRSF12; Protein WSL-1; LARD; Tumor Necrosis Factor Receptor Superfamily Member 25 Deletion Mutant; DDR3; Tumor Necrosis Factor Receptor Superfamily, Member 25; DR3; Death Domain Receptor 3 Soluble Form; WSL-LR; Apoptosis Inducing Receptor; TRAMP; Death Receptor Beta; WSL-1; Death Receptor 3; APO-3; Protein WSL; TR3; Apo-3; Tumor Necrosis Factor Receptor Superfamily, Member 12 (Translocating Chain-Association Membrane Protein); APO3; Tumor Necrosis Factor Receptor Superfamily Member 25; WSL1; Lymphocyte-Associated Receptor Of Death; WSL; Apoptosis-Mediating Receptor TRAMP; TNF Receptor Superfamily Member 25; Apoptosis-Inducing Receptor AIR
Species:
Human
Source:
HEK293
Cat. No.: HY-RS14813
Target:
Research Areas:
TNFRSF25 Human Pre-designed siRNA Set A contains three designed siRNAs for TNFRSF25 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P72666
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF25; Apoptosis-Mediating Receptor DR3; Prev. TNFRSF12; Protein WSL-1; LARD; Tumor Necrosis Factor Receptor Superfamily Member 25 Deletion Mutant; DDR3; Tumor Necrosis Factor Receptor Superfamily, Member 25; DR3; Death Domain Receptor 3 Soluble Form; WSL-LR; Apoptosis Inducing Receptor; TRAMP; Death Receptor Beta; WSL-1; Death Receptor 3; APO-3; Protein WSL; TR3; Apo-3; Tumor Necrosis Factor Receptor Superfamily, Member 12 (Translocating Chain-Association Membrane Protein); APO3; Tumor Necrosis Factor Receptor Superfamily Member 25; WSL1; Lymphocyte-Associated Receptor Of Death; WSL; Apoptosis-Mediating Receptor TRAMP; TNF Receptor Superfamily Member 25; Apoptosis-Inducing Receptor AIR
Species:
Human
Source:
HEK293
Cat. No.: HY-P990876A
Synonyms: PF-06480605; RVT-3101
Target:
Research Areas:
Afimkibart (PF-06480605; RVT-3101) is a humanized monoclonal antibody targeting TL1A (TNFSF15). Afimkibart blocks the TL1A‑DR3 signaling axis by neutralizing the TL1A ligand, inhibits the release of pro-inflammatory cytokines, suppresses NF-κB activation and IFN-γ production, and simultaneously attenuates fibroblast activation and fibrosis progression associated with this pathway. The Fc region of Afimkibart contains the mutations L234A, L235A, and G237A, which are designed to reduce the binding of the antibody to FcγR and C1q, thereby attenuating or eliminating the antibody’s ADCC and CDC effector functions. Afimkibart is applicable to research on immune inflammation-related conditions, such as ulcerative colitis .
Cat. No.: HY-175177
Xiap-casp7 PPI-IN-1 is a reversible XIAP: CASP7 inhibitor with specifically disrupting the interaction between XIAP and CASP7. XIAP-CASP7 PPI-IN-1 selectively induce MCF-7 and other caspase-3 down-regulation (CASP3/DR) triple-negative breast cancer cell apoptosis. XIAP-CASP7 PPI-IN-1 overcomes chemoresistance via down-regulating β-catenin and its associated ABC transporters in Paclitaxel (HY-B0015)-resistant MCF-7 cells. XIAP-CASP7 PPI-IN-1 can be used for the study of breast cancer .
Cat. No.: HY-RS19293
Target:
Research Areas:
Tnfrsf25 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tnfrsf25 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P701323
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor Necrosis Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of Apoptosis; APO3L; Tumor Necrosis Factor Ligand 4A; Tumor Necrosis Factor Ligand Superfamily Member 12; HCG1991317, Isoform CRA_a; Tumor Necrosis Factor (Ligand) Superfamily, Member 12; APO3/DR3 Ligand; TNF-Related Weak Inducer Of Apoptosis; TNFSF12 Protein; APO3 Ligand
Species:
Mouse
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
