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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
Delta variant
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "Delta variant" in MCE Product Catalog:
5
Category:
Simaroubaceae Extract Ailanthus altissima (Mill.) Swingle Terpenoids Diterpenoids Plants Disease Research Fields Inflammation/Immunology
Target:
2
1
1 Cited Publications
Cat. No.: HY-P70248
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ESR1; Estrogen Receptor Alpha Delta 4*,5,6,7*/654 Isoform; Prev. ESR; Estrogen Receptor Alpha 3*,4,5,6,7,8*/1032 Isoform; ER-Alpha; Estrogen Receptor Alpha 3*,4,5,6,7,8*/1068 Isoform; ER; Estrogen Receptor Alpha 3*,4,5,6,7,8*/984 Isoform; Nuclear Receptor Subfamily 3 Group A Member 1; Hippocampal Estrogen Receptor Alpha Isoform TADDI; Estradiol Receptor; Estrogen Receptor Alpha 2*,3,4,5,6,7*,8* Isoform; NR3A1; Estrogen Receptor Alpha 3*,4,5,6,7*/765 Isoform; Estrogen Receptor; Estrogen Receptor Alpha 3*,4,5,6,7*/822 Isoform; Era; Estrogen Receptor Alpha Delta 3*4,5*,7 Isoform; Oestrogen Receptor Alpha; Estrogen Receptor Alpha Delta 4,5,6,7 Isoform; Estrogen Receptor Alpha; Estrogen Receptor Alpha Delta 3*4*,7 Isoform; E2 Receptor Alpha; Estrogen Receptor Alpha E1-N2-E2-1-2 variant; Estrogen Receptor Alpha Delta 2*,3,4,5,6,7*/834 Hypothalamic Isoform; Estrogen Receptor Alpha Delta 4,5,7 Isoform; Estrogen Receptor Alpha Delta 3*,4,5,6,7*/775 Hypothalamic Isoform; Estrogen Receptor Alpha Delta 4 +49 Isoform; Estrogen Receptor Alpha Delta 1*,2,3*/663 Choroid Plexus Isoform; Estrogen Receptor Alpha E1-N1-E2-1 variant; Estrogen Receptor Alpha Delta 4,7*,8*/581 Hypothalamic Isoform; Estrogen Receptor Alpha E1-N2-E2-2 variant; Estrogen Receptor Alpha Delta 4*,5,6*/481 Hypothalamic Isoform; Estrogen Receptor Alpha Delta 6,7 Isoform; Estrogen Receptor Alpha Delta 3*,4,5,6,7*, 8*/912 Isoform; Estrogen Receptor Alpha E1-E2-1-2 variant; Estrogen Receptor Alpha Delta 3*,4,5,6,7*,8*/941 Isoform; Estrogen Receptor Alpha E1-E2-2 variant; Estrogen Receptor Alpha Delta 3*,4,5,6,7,8*/1029 Isoform; Estrogen Receptor Alpha Splice variant; Estrogen Receptor Alpha Delta 3*,4,5,6,7*/819-2 Isoform; Estrogen Receptor Alpha E1-1-2 variant; Estrogen Receptor Alpha Delta 3*,4,5,6,7,8*/969 Isoform; Estrogen Receptor Alpha E1-N2-E2-1-2; Estrogen Receptor Alpha Delta 3*,4,5,6,7,8*/984 Isoform; Estrogen Receptor Alpha E1-2 variant; Estrogen Receptor Alpha Delta 2*,3,4,5,6,7*/963 Isoform; Estrogen Receptor Alpha E1-E2-1-2; Estrogen Receptor Alpha Superior Frontal Gyrus Isoform; Estrogen Nuclear Receptor Alpha; Estrogen Receptor Alpha Delta 4*,5,6,7,8*/918 Isoform; Estrogen Receptor Protein; Estrogen Receptor Alpha Delta 4*,5,6,7,8*/885 Isoform; Alternative Protein ESR1; Estrogen Receptor Alpha Delta 4*,5,6,7,8*/901 Isoform; ESTRR; Estrogen Receptor Alpha Delta 4*,5,6,7*/633 Isoform; ESRA; Estrogen Receptor 1; Estrogen Receptor Alpha Delta 2*,3,4,5,6,7 Isoform
Species:
Human
Source:
E. coli
Synonyms: WU-04
Iscartrelvir (WU-04) is a non-covalent inhibitor of SARS-CoV-2, targeting the 3CLpro protein. Iscartrelvir has high inhibitory effect on the 3CLpro protein of 6 SARS-CoV-2 variants (Alpha, Beta, Gamma, Delta, Lambda and Omicron) and 2 coronaviruses (SARS-CoV and MERS-CoV) .
Cat. No.: HY-174385
SARS-CoV-2-IN-114 (Compound 36) is an antiviral agent. SARS-CoV-2-IN-114 exhibits significant antiviral activity against both the SARS-CoV-2 original strain and the Delta variant. SARS-CoV-2-IN-114 has an EC50 of 0.29 μM for inhibiting CPE of the SARS-CoV-2 original strain, and that for the Delta variant is 5.77 μM. SARS-CoV-2-IN-114 has low cytotoxicity and can be used in coronavirus research .
Cat. No.: HY-151265
CAS No.: 2719679-31-7
MMT5-14 is a remdesivir analogue with a higher antiviral activity in four variants of SARS-CoV-2 than Remdesivir (HY-104077). MMT5-14 inhibits SARS-CoV-2, α, β, γ and δ variants with EC50s of 0.4, 2.5, 15.9, 1.7 and 5.6 μM, respectively. MMT5-14 can be used for the research of COVID-19 .
Cat. No.: HY-178291
CAS No.: 104959-32-2
2-Chloro-2′-deoxyadenosine monophosphate is an anticoronavirus agent. It exhibits significant inhibitory effects against wild-type novel coronavirus, novel coronavirus variants (Beta, Delta, and Omicron strains), and other coronaviruses such as human coronavirus 229E, human coronavirus OC43, human coronavirus NL63, and mouse coronavirus MHV .
Cat. No.: HY-168917
CAS No.: 149934-19-0
Synonyms: 9-AMN
Target:
Research Areas:
9-Aminominocycline (9-AMN) is the inhibitor for SARS-CoV-2 papain-like protease (SARS-CoV-2 PLpro), inhibits its deubiquitination (DUB) activity and protease activity with IC50 of 4.55 µM and 4.15 µM. 9-Aminominocycline inhibits the SARS-CoV variants Delta and Omicron replication in Calu-3 cell with IC50 of 1.04 µM and 2.35 µM .
Cat. No.: HY-163913
SARS-CoV-IN-5 (compound 49) is a highly selective, nonpeptidic and noncovalent 3CL pro inhibitor with IC50s of 38 nM, 21.1 nM and 86 nM for 3CL pro of SARS-CoV-1, SARS-CoV-2, Bat coronavirus WIV1, respectively. SARS-CoV-IN-5 inhibits the replication of the SARS-CoV-2 delta variant with an EC50 of 0.272 μM. SARS-CoV-IN-5 significantly reduces the lung viral copies in a K18-hACE2 transgenic mouse model. SARS-CoV-IN-5 has good target-specific and potential broad-spectrum anticoronavirus activities against SARS-CoV-1, WIV1, MERS, HCoV-OC43, HCoV-229E, and HKU9 .
Cat. No.: HY-P704244
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PPARD; Nuclear Hormone Receptor 1; Peroxisome Proliferator Activated Receptor Delta; PPAR-Delta; NR1C2; PPAR-Beta; PPARB; NUCI; NUC1; Peroxisome Proliferator-Activated Nuclear Receptor Beta/Delta variant 2; Peroxisome Proliferator-Activated Receptor Delta
Species:
Human
Source:
E. coli
Cat. No.: HY-P7S0363
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPARD; Nuclear Hormone Receptor 1; Peroxisome Proliferator Activated Receptor Delta; PPAR-Delta; NR1C2; PPAR-Beta; PPARB; NUCI; NUC1; Peroxisome Proliferator-Activated Nuclear Receptor Beta/Delta variant 2; Peroxisome Proliferator-Activated Receptor Delta; Peroxisome Proliferative Activated Receptor, Delta, Isoform CRA_b; NUCII; Peroxisome Proliferative Activated Receptor, Delta; FAAR; Peroxisome Proliferator Activated Receptor Beta; Peroxisome Proliferator-Activated Receptor Beta; Alternative Protein PPARD; Nuclear Receptor Subfamily 1 Group C Member 2; PPARD/MYO1D Fusion
Species:
Human
Source:
HEK293
Cat. No.: HY-P72069
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ABCC1; ATP-Binding Cassette Sub-Family C Member 1; Prev. MRP1; LTC4 Transporter; Prev. MRP; ATP-Binding Cassette Transporter variant ABCC1Delta-Ex25; Glutathione-S-Conjugate-Translocating ATPase ABCC1; ATP-Binding Cassette Transporter variant ABCC1Delta-E
Species:
Human
Source:
E. coli
Cat. No.: HY-P701355
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ABCC1; ATP-Binding Cassette Sub-Family C Member 1; Prev. MRP1; LTC4 Transporter; Prev. MRP; ATP-Binding Cassette Transporter variant ABCC1Delta-Ex25; Glutathione-S-Conjugate-Translocating ATPase ABCC1; ATP-Binding Cassette Transporter variant ABCC1Delta-E
Species:
Bovine
Source:
HEK293
Cat. No.: HY-P706328
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ESR1; Estrogen Receptor Alpha Delta 4*,5,6,7*/654 Isoform; Prev. ESR; Estrogen Receptor Alpha 3*,4,5,6,7,8*/1032 Isoform; ER-Alpha; Estrogen Receptor Alpha 3*,4,5,6,7,8*/1068 Isoform; ER; Estrogen Receptor Alpha 3*,4,5,6,7,8*/984 Isoform; Nuclear Receptor Subfamily 3 Group A Member 1; Hippocampal Estrogen Receptor Alpha Isoform TADDI; Estradiol Receptor; Estrogen Receptor Alpha 2*,3,4,5,6,7*,8* Isoform; NR3A1; Estrogen Receptor Alpha 3*,4,5,6,7*/765 Isoform; Estrogen Receptor; Estrogen Receptor Alpha 3*,4,5,6,7*/822 Isoform; Era; Estrogen Receptor Alpha Delta 3*4,5*,7 Isoform; Oestrogen Receptor Alpha; Estrogen Receptor Alpha Delta 4,5,6,7 Isoform; Estrogen Receptor Alpha; Estrogen Receptor Alpha Delta 3*4*,7 Isoform; E2 Receptor Alpha; Estrogen Receptor Alpha E1-N2-E2-1-2 variant; Estrogen Receptor Alpha Delta 2*,3,4,5,6,7*/834 Hypothalamic Isoform; Estrogen Receptor Alpha Delta 4,5,7 Isoform; Estrogen Receptor Alpha Delta 3*,4,5,6,7*/775 Hypothalamic Isoform; Estrogen Receptor Alpha Delta 4 +49 Isoform; Estrogen Receptor Alpha Delta 1*,2,3*/663 Choroid Plexus Isoform; Estrogen Receptor Alpha E1-N1-E2-1 variant; Estrogen Receptor Alpha Delta 4,7*,8*/581 Hypothalamic Isoform; Estrogen Receptor Alpha E1-N2-E2-2 variant; Estrogen Receptor Alpha Delta 4*,5,6*/481 Hypothalamic Isoform; Estrogen Receptor Alpha Delta 6,7 Isoform; Estrogen Receptor Alpha Delta 3*,4,5,6,7*, 8*/912 Isoform; Estrogen Receptor Alpha E1-E2-1-2 variant; Estrogen Receptor Alpha Delta 3*,4,5,6,7*,8*/941 Isoform; Estrogen Receptor Alpha E1-E2-2 variant; Estrogen Receptor Alpha Delta 3*,4,5,6,7,8*/1029 Isoform; Estrogen Receptor Alpha Splice variant; Estrogen Receptor Alpha Delta 3*,4,5,6,7*/819-2 Isoform; Estrogen Receptor Alpha E1-1-2 variant; Estrogen Receptor Alpha Delta 3*,4,5,6,7,8*/969 Isoform; Estrogen Receptor Alpha E1-N2-E2-1-2; Estrogen Receptor Alpha Delta 3*,4,5,6,7,8*/984 Isoform; Estrogen Receptor Alpha E1-2 variant; Estrogen Receptor Alpha Delta 2*,3,4,5,6,7*/963 Isoform; Estrogen Receptor Alpha E1-E2-1-2; Estrogen Receptor Alpha Superior Frontal Gyrus Isoform; Estrogen Nuclear Receptor Alpha; Estrogen Receptor Alpha Delta 4*,5,6,7,8*/918 Isoform; Estrogen Receptor Protein; Estrogen Receptor Alpha Delta 4*,5,6,7,8*/885 Isoform; Alternative Protein ESR1; Estrogen Receptor Alpha Delta 4*,5,6,7,8*/901 Isoform; ESTRR; Estrogen Receptor Alpha Delta 4*,5,6,7*/633 Isoform; ESRA; Estrogen Receptor 1; Estrogen Receptor Alpha Delta 2*,3,4,5,6,7 Isoform
Species:
Human
Source:
E. coli
Cat. No.: HY-182894
Target:
Research Areas:
MR1-114 is an orally active SARS-CoV-2 papain-like protease (PLpro) inhibitor with an IC50 of 0.037 μM. As a broad-spectrum inhibitor, MR1-114 maintains submicromolar activity against SARS-CoV-2 Delta, Omicron B.1.1.529 and Omicron BA.5 variants, with EC50 values of 0.18 μM, 0.39 μM and 0.20 μM, respectively. MR1-114 can be used for the research of coronavirus disease 2019 (SARS-CoV-2 infection) .
Cat. No.: HY-181661
Target:
Research Areas:
YL1004 is a potent, selective and orally active noncovalent inhibitor of SARS-CoV-2 papain-like protease (PL pro). YL1004 shows an IC50 of 17.5 nM and a Ki of 2.3 nM against PL pro, with an in vitro anti-SARS-CoV-2 EC50 of 0.08 μM-1.37 μM. YL1004 suppresses the proteolytic activity of PL pro and blocks its deubiquitinating and deISGylating effects to restore host innate antiviral immune signaling. YL1004 inhibits the replication of wild-type, Delta, Omicron variants and nirmatrelvir-resistant strains of SARS-CoV-2. YL1004 can be used for the research of COVID-19 (SARS-CoV-2 infection) .
Cat. No.: HY-175829
SARS-CoV-2-IN-119 (Compound A28) is a SARS-CoV-2 fusion inhibitor. SARS-CoV-2-IN-119 strongly inhibits Omicron entry with an EC50s of 1.95 and 1.08 μM for pOmicron (BA.2.86.1) and wild Omicron. SARS-CoV-2-IN-119 also has antiviral activities against wild SARS-CoV-2 and other variants, such as pseudotyped Delta SARS-CoV-2, pOmicron (BA.4) and (KP.3). SARS-CoV-2-IN-119 directly interferes with Omicron S2-mediated viral membrane fusion to block Omicron virus into host cells. SARS-CoV-2-IN-119 can be used for COVID-19 research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
