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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
Elsunersen
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "Elsunersen" in MCE Product Catalog:
Cat. No.: HY-177629
CAS No.: 2756001-75-7
Synonyms: PRAX-222
Target:
Research Areas:
Elsunersen (PRAX‑222) is a gapmer antisense oligonucleotide targeting SCN2A mRNA. Elsunersen reduces the protein level of the voltage-gated sodium channel NaV1.2 by degrading SCN2A mRNA, alleviating neuronal network hyperexcitability . Elsunersen combined with sodium channel blockers terminates refractory status epilepticus and reduces seizure frequency. Elsunersen can be used in research related to epileptic encephalopathy .
Cat. No.: HY-177629A
Synonyms: PRAX-222 sodium
Target:
Research Areas:
Elsunersen sodium (PRAX‑222 sodium) is a gapmer antisense oligonucleotide targeting SCN2A mRNA. Elsunersen sodium reduces the protein level of the voltage-gated sodium channel NaV1.2 by degrading SCN2A mRNA, alleviating neuronal network hyperexcitability . Elsunersen sodium combined with sodium channel blockers terminates refractory status epilepticus and reduces seizure frequency. Elsunersen sodium can be used in research related to epileptic encephalopathy .
Cat. No.: HY-177629C
Research Areas:
FAM labled Elsunersen sodium refers to Elsunersen sodium (HY-177629A) tagged with the fluorescent dye FAM. Elsunersen sodium (PRAX‑222 sodium) is a gapmer antisense oligonucleotide targeting SCN2A mRNA. Elsunersen sodium reduces the protein level of the voltage-gated sodium channel NaV1.2 by degrading SCN2A mRNA, alleviating neuronal network hyperexcitability . Elsunersen sodium combined with sodium channel blockers terminates refractory status epilepticus and reduces seizure frequency. Elsunersen sodium can be used in research related to epileptic encephalopathy .
Cat. No.: HY-177629B
Target:
Research Areas:
Elsunersen sodium scrambled negative control is a scrambled negative control for Elsunersen sodium (HY-177629A). Elsunersen sodium (PRAX‑222 sodium) is a gapmer antisense oligonucleotide targeting SCN2A mRNA. Elsunersen sodium reduces the protein level of the voltage-gated sodium channel NaV1.2 by degrading SCN2A mRNA, alleviating neuronal network hyperexcitability . Elsunersen sodium combined with sodium channel blockers terminates refractory status epilepticus and reduces seizure frequency. Elsunersen sodium can be used in research related to epileptic encephalopathy .
Cat. No.: HY-177629D
Research Areas:
Cy3 labled Elsunersen sodium refers to Elsunersen sodium (HY-177629A) tagged with the fluorescent dye Cy3 (HY-D0822). Elsunersen sodium (PRAX‑222 sodium) is a gapmer antisense oligonucleotide targeting SCN2A mRNA. Elsunersen sodium reduces the protein level of the voltage-gated sodium channel NaV1.2 by degrading SCN2A mRNA, alleviating neuronal network hyperexcitability . Elsunersen sodium combined with sodium channel blockers terminates refractory status epilepticus and reduces seizure frequency. Elsunersen sodium can be used in research related to epileptic encephalopathy .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
