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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
Exatecan Analog
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "Exatecan Analog" in MCE Product Catalog:
Cat. No.: HY-128995AS
Purity: 95.08%
Synonyms: Glycyl-DX-8951-d5 hydrochloride; Exatecan Analog 2-d5 hydrochloride
Cat. No.: HY-W021377
CAS No.: 182182-31-6
Target:
Research Areas:
Exatecan Intermediate 2 (Compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
Cat. No.: HY-128995A
CAS No.: 1883333-57-0
Synonyms: Glycyl-DX-8951 TFA; Exatecan Analog 2 TFA
Target:
Research Areas:
Glycyl-Exatecan TFA (G-DX-8951 TFA) is a Topoisomerase I inhibitor. Glycyl-Exatecan TFA exhibits weaker in vitro cytotoxicity than DX-8951 (HY-13631), and can further release DX-8951 in vivo. Glycyl-Exatecan TFA can be used in studies related to Exatecan metabolism and antitumor drug delivery .
Cat. No.: HY-W021377B
CAS No.: 2436720-50-0
Target:
Research Areas:
Exatecan Intermediate 4 (Compound 14f) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
Cat. No.: HY-W021377A
CAS No.: 2437603-23-9
Target:
Research Areas:
Exatecan Intermediate 2 hydrochloride (Compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
Cat. No.: HY-178315
CAS No.: 2766214-00-8
Target:
Research Areas:
Exatecan analog 38 is a camptothecin derivative with potent topoisomerase I inhibitory activity. Exatecan analog 38 can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. Exatecan analog 38 can be used for cancer research .
Cat. No.: HY-48878
Target:
Research Areas:
Exatecan analog 36 is a analog of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM) .
Cat. No.: HY-178290
CAS No.: 2766214-01-9
Research Areas:
MC-Gly-Gly-Phe-Exatecan analog 38 (Compound L-II-4) is part of an antibody-drug conjugate (ADC), consisting of an ADC toxicant molecule and an ADC linker. MC-Gly-Gly-Phe-Exatecan analog 38 can be used to synthesize ADCs (such as ADC-II-15 and ADC-III-13). MC-Gly-Gly-Phe-Exatecan analog 38 can also be used in cancer research (ADC Cytotoxin: HY-178315, ADC Linker: HY-44235) .
Cat. No.: HY-13631G
CAS No.: 1599439-47-0
Target:
Research Areas:
Exatecan analog 13 is a analog of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50 = 2.2 μM) .
Cat. No.: HY-W021377C
Target:
Research Areas:
Exatecan Intermediate 4 dihydrochloride (Compound 14f) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
Cat. No.: HY-128995
CAS No.: 849479-60-3
Synonyms: Glycyl-DX-8951; Exatecan Analog 2
Target:
Research Areas:
Glycyl-Exatecan (G-DX-8951) is a Topoisomerase I inhibitor. Glycyl-Exatecan exhibits weaker in vitro cytotoxicity than DX-8951 (HY-13631), and can further release DX-8951 in vivo. Glycyl-Exatecan can be used in studies related to Exatecan metabolism and antitumor drug delivery .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
