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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
FFAR4
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "FFAR4" in MCE Product Catalog:
3
Category:
Cat. No.: HY-RS04877
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Research Areas:
FFAR4 Human Pre-designed siRNA Set A contains three designed siRNAs for FFAR4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Icosabutate is an orally active engineered fatty acid and a dual FFAR1/FFAR4 (GPR40/GPR120) agonist with EC50 values of 10 μM and 15.5 μM, respectively. Icosabutate acts as a partial agonist of PPAR-α, with an EC50 of 208 nM. Icosabutate inhibits the arachidonic acid cascade and exhibits antioxidant and anti-apoptotic activities. Icosabutate can be used in the research of nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis, and atherosclerosis [4].
Cat. No.: HY-N3977
CAS No.: 80557-12-6
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Cat. No.: HY-162689
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GprA is a new synthetic agonist of G-protein-coupled receptor 120/free fatty acid receptor 4 (GPR120/FFAR4), with an AC50 of 203 nM on human GPR120 full isoform. GprA can be used in the research for NAFLD .
Cat. No.: HY-RS18817
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Ffar4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ffar4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-164870
CAS No.: 2839486-16-5
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FFAR1/FFAR4 agonist-1 (compound 83) is a FFAR1/FFAR4 agonist with the EC50 of 1 nM A and 4nM for FFAR1 and FFAR4, respectively. FFAR1/FFAR4 agonist-1 can be used for study of glycemic control .
Cat. No.: HY-185937
CAS No.: 3110207-82-1
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FFAR4 agonist-1 is an orally active, selective agonist of FFAR4. FFAR4 agonist-1 improves glucose tolerance, reduces blood glucose levels and promotes insulin secretion. FFAR4 agonist-1 can be used in the research of type 2 diabetes .
Cat. No.: HY-RS25307
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Ffar4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ffar4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W592871R
CAS No.: 765-01-5
Synonyms: 10-HDA (Standard); Queen Bee Acid (Standard)
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Target:
Cat. No.: HY-121212R
CAS No.: 1253909-57-7
Research Areas:
Icosabutate (Standard) is the analytical standard of Icosabutate (HY-121212). This product is intended for research and analytical applications. Icosabutate is an orally active engineered fatty acid and a dual FFAR1/FFAR4 (GPR40/GPR120) agonist with EC50 values of 10 μM and 15.5 μM, respectively. Icosabutate acts as a partial agonist of PPAR-α, with an EC50 of 208 nM. Icosabutate inhibits the arachidonic acid cascade and exhibits antioxidant and anti-apoptotic activities. Icosabutate can be used in the research of nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis, and atherosclerosis [4].
Cat. No.: HY-167216
CAS No.: 215997-93-6
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Research Areas:
PSB-15160 is a human GPR84 agonist with EC50 values of 0.0800 μM and 4.33 μM, and selectivity versus FFAR1, FFAR4, and arylhydrocarbon receptor. PSB-15160 exhibits biased agonism, ago-allosteric action, and structure-activity relationships differing between cAMP and β-arrestin assays. PSB-15160 shows increased stability relative to the lead structure 3,3'-diindolylmethane .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
