17 Results for "

Fluvastatin

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "Fluvastatin" in MCE Product Catalog:

21
21 Publications Verification
Cat. No.: HY-14664
CAS No.: 93957-54-1
Purity:  98.49%
Synonyms: XU 62-320 free acid
Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .
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21
21 Publications Verification
Cat. No.: HY-14664A
CAS No.: 93957-55-2
Purity:  99.94%
Synonyms: XU 62-320
Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin sodium protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .
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Cat. No.: HY-14664AS
Purity:  98.98%
Synonyms: XU 62-320-d6
Fluvastatin-d6 (sodium) is deuterium labeled Fluvastatin sodium. Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.
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Cat. No.: HY-135358
CAS No.: 1160169-39-0
Synonyms: 3-Hydroxy-5-Keto Fluvastatin
Research Areas:  

Cardiovascular Disease

(Rac)-5-Keto Fluvastatin (3-Hydroxy-5-Keto Fluvastatin) is an impurity of Fluvastatin (XU 62320). Fluvastatin is a HMG-CoA reductase inhibitor with an IC50 of 8 nM .
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Cat. No.: HY-14664AR
CAS No.: 93957-55-2
Synonyms: XU 62-320 (Standard)
Fluvastatin (sodium) (Standard) is the analytical standard of Fluvastatin (sodium). This product is intended for research and analytical applications. Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin sodium protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .
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Cat. No.: HY-14664R
CAS No.: 93957-54-1
Synonyms: XU 62-320 free acid (Standard)
Fluvastatin (Standard) is the analytical standard of Fluvastatin. This product is intended for research and analytical applications. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .
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Cat. No.: HY-14664B
CAS No.: 155229-75-7
Synonyms: (3R,5S)-XU 62-320 free acid
(3R,5S)-Fluvastatin is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .
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Cat. No.: HY-14664C
CAS No.: 94061-81-1
Purity:  98.16%
Synonyms: (3S,5R)-XU 62-320
Research Areas:  

Cardiovascular Disease Cancer

(3S,5R)-Fluvastatin sodium ((3S,5R)-XU 62-320) is the (3S,5R)-enantiomer of Fluvastatin. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .
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Cat. No.: HY-14664CS
CAS No.: 2249799-35-5
Purity:  ≥98.0%
Synonyms: (3S,5R)-XU 62-320-d6
(3S,5R)-Fluvastatin-d6 (sodium)?is the deuterium labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive?HMG-CoA reductase?inhibitor with an IC50?of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .
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Cat. No.: HY-Z5058A
CAS No.: 194935-01-8
Target:  

Drug Isomer

Research Areas:  

Others

(3S,5S)-Fluvastatin sodium is the isomer of Fluvastatin sodium (HY-14664A). Fluvastatin sodium is a first fully synthetic, competitive HMG-CoA reductase inhibitor .
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Cat. No.: HY-137213
CAS No.: 94061-83-3
Research Areas:  

Inflammation/Immunology

Fluvastatin lactone is the lactone form of Fluvastatin (HY-14664) detected in human plasma after administration. It competitively or mixed-type inhibits CYP2C9-catalyzed S-Warfarin 7-hydroxylation, and induces myotoxicity in a concentration- and time-dependent manner in rat and primary human skeletal muscle cells, reducing the number of surviving myotubes and causing morphological changes in myotubes. Fluvastatin lactone can be used for studies on myotoxicity and statin-induced myotoxicity .
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Cat. No.: HY-14664D
CAS No.: 201541-53-9
Synonyms: XU 62-320 monohydrate
Fluvastatin (XU 62-320) sodium monohydrate is a first fully synthetic, competitive HMG-CoA reductaseinhibitor with an IC50 of 8 nM. Fluvastatin (sodium monohydrate) protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .
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Cat. No.: HY-137390A
CAS No.: 1009811-63-5
(3S,5R)-Fluvastatin (potassium) is a synthetic hypolipidemic drug that inhibits HMG-CoA reductase activity. (3S,5R)-Fluvastatin (potassium) has similar antioxidative effects on copper ion-induced LDL oxidation compared to its 3R,5S enantiomer. (3S,5R)-Fluvastatin (potassium) and its metabolites demonstrate a potential to exhibit anti-atherosclerotic effects through their antioxidative activities. (3S,5R)-Fluvastatin (potassium) is clinically utilized as part of a racemic mixture for reducing plasma cholesterol levels.
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Cat. No.: HY-14664F
CAS No.: 94061-80-0
Purity:  99.18%
Synonyms: (3R,5S)-XU 62-320
Research Areas:  

Cancer

(3R,5S)-Fluvastatin ((3R,5S)-XU 62-320) sodium is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .
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Cat. No.: HY-14664DS
CAS No.: 2249799-34-4
Synonyms: (3S,5R)-XU 62-320-d6 free acid
(3S,5R)-Fluvastatin-d6 is the deuterium labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive?HMG-CoA reductase?inhibitor with an IC50?of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .
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Cat. No.: HY-162410
Target:  

MDM-2/p53

Research Areas:  

Cancer

Fluplatin is a prodrug composed of cisplatin and fluvastatin. Fluplatin has antitumor activity .
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Cat. No.: HY-Z5058S
CAS No.: 1260178-87-7
Synonyms: (3R,5S)-XU 62-320-d7
(3R,5S)-Fluvastatin-d7 (sodium) is the deuterium labeled (3R,5S)-Fluvastatin sodium .
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