2 Results for "

GL261

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "GL261" in MCE Product Catalog:

Cat. No.: HY-16785
CAS No.: 1093130-72-3
Synonyms: INXN-1001; RG-115932
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Veledimex (INXN-1001), a synthetic analog of the insect molting hormone ecdysone, is an orally active activator ligand for a proprietary gene therapy promoter system. Veledimex can be used to activate certain genes using the ecdysone receptor (EcR)-based inducible gene regulation system, the RheoSwitch Therapeutic System (RTS). Veledimex can cross blood-brain barrier (BBB) in both orthotopic GL-261 mice and cynomolgus monkeys .
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Cat. No.: HY-P991419

Target:  

VEGFR

Research Areas:  

Cancer

MSB-0254 is a human monoclonal antibody (mAb) targeting VEGFR2/KDR/CD309. MSB-0254 inhibits the invasion, migration, and vascular mimetic (VM) formation of U251 and primary glioma cells. MSB-0254 inhibits the growth of U251 and GL261 cell transplanted tumors. MSB-0254 reduces the expression of CD34, VEGFR2, Ki67, MMP2, MMP9, and CD34/PAS. MSB-0254 can be used in advanced solid tumors research .
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