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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
Gram-negative microorganisms
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "Gram-negative microorganisms" in MCE Product Catalog:
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35
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25
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Kanamycin disulfate (Kanamycin A disulfate) is an antibacterial agent. Kanamycin disulfate blocks Kir4.1 channels. Kanamycin disulfate inhibits bacterial mRNA translation and exerts bactericidal effects against Gram-positive, Gram-negative, and acid-resistant microorganisms. Kanamycin disulfate produces ROS and superoxide and induces caspase-3-mediated apoptosis. Kanamycin disulfate inhibits biofilms and reduces persister bacteria, and reduces Mycobacterium tuberculosis within macrophages. Kanamycin disulfate can be used in research on bacterial infections, urinary tract infections, tuberculosis, and Staphylococcus aureus-induced peritonitis .
Synonyms: Erythromycin Cyclocarbonate
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Davercin (Erythromycin Cyclocarbonate), derivative of Erythromycin, which is active against Gram-positive and some Gram-negative microorganisms.
Cat. No.: HY-B0712S
CAS No.: 1132650-38-4
Synonyms: Ro 13-9904-d3 disodium
Cat. No.: HY-W016473
CAS No.: 828-51-3
Cat. No.: HY-P1791
CAS No.: 146897-68-9
Synonyms: Lactoferricin B; Lfcin B
Cat. No.: HY-P1791B
CAS No.: 2828433-30-1
Synonyms: Lactoferricin B acetate; Lfcin B acetate
Cat. No.: HY-108988
CAS No.: 1622253-00-2
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Albicidin is a peptide antibiotic with phytotoxic activity. Albicidin potently inhibits bacterial and plant DNA gyrase at nanomolar concentrations, blocks DNA replication, and exhibits excellent antibacterial efficacy against multidrug-resistant bacteria. Albicidin possesses bactericidal activity against Gram-positive and Gram-negative microorganisms, and acts as a virulence factor for the systemic plant infection by Xanthomonas albilineans. Albicidin can be used in studies related to bacterial infections and sugarcane leaf blight .
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Cat. No.: HY-123436
CAS No.: 84745-01-7
Category:
Target:
Cat. No.: HY-100584R
CAS No.: 55224-05-0
Synonyms: Erythromycin Cyclocarbonate (Standard)
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Research Areas:
Davercin (Standard) (Erythromycin Cyclocarbonate (Standard)) is the analytical standard of Davercin (HY-100584). This product is intended for research and analytical applications. Davercin (Erythromycin Cyclocarbonate), derivative of Erythromycin, which is active against Gram-positive and some Gram-negative microorganisms.
Cat. No.: HY-113703
CAS No.: 99734-97-1
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PD117588 is a quinolone antibacterial agent with a broad range of antibacterial activity. PD117588 exhibits excellent activity against a variety of Gram-positive and Gram-negative bacteria from cancer patients, especially against all Gram-positive strains, including methicillin-resistant Staphylococcus aureus, coagulase-negative Staphylococci, and Enterococci. PD117588 is also very effective against most Gram-negative bacilli, although ciprofloxacin shows stronger activity against Pseudomonas aeruginosa. Compared with other quinolone antibiotics, the minimum inhibitory concentration of PD117588 outperforms most of the tested microorganisms, including imipenem and ceftazidime .
Cat. No.: HY-120733
CAS No.: 1205538-83-5
Synonyms: FKI-4905
Target:
Cat. No.: HY-147505
CAS No.: 2412142-93-7
Antitubercular agent-21 (Compound 15) is an antitubercular agent with an MIC of o.4 µg/mL against M. tuberculosis H37Rv. Antitubercular agent-21 exhibits lower activity against other microorganism such as bacteria gram-positive, gram-negative or fungi. Antitubercular agent-21 shows low cytotoxicity .
Cat. No.: HY-16566AR
CAS No.: 25389-94-0
Synonyms: Kanamycin A sulfate (Standard)
Cat. No.: HY-100584S
Synonyms: Erythromycin Cyclocarbonate-13C,d3
Cat. No.: HY-106946
CAS No.: 147293-55-8
Target:
E 5065 is an orally active antibacterial agent. E 5065 exhibits potent in vitro activity against Gram-negative microorganisms, Gram-positive cocci, and anaerobes. E 5065 exhibits an MIC90 of 0.5 μg/mL against Clostridium spp. E 5065 provides protection against experimental infections caused by P. aeruginosa .
Cat. No.: HY-W923278
CAS No.: 73547-70-3
Synonyms: GR20263 dihydrochloride
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Research Areas:
Ceftazidime (GR20263) dihydrochloride is a cephalosporin β-lactam antibiotic. Ceftazidime dihydrochloride exhibits activity against susceptible Enterobacteriaceae, multidrug-resistant Gram-negative bacteria, Pseudomonas aeruginosa, and bacteria producing Ambler class A, C, and some class D β-lactamases, but shows no activity against microorganisms producing metallo-β-lactamases. Ceftazidime dihydrochloride reduces bacterial loads in mouse models of splenic, hepatic, and thigh infections, but has low efficacy against ESBL- and KPC-producing Enterobacteriaceae. Ceftazidime dihydrochloride can be used in research related to complicated urinary tract infections, complicated intra-abdominal infections, hospital-acquired pneumonia, carbapenemase-producing Klebsiella pneumoniae infections, carbapenem-resistant Enterobacterales infections, and severe Gram-negative bacterial infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
