17 Results for "

Graves'

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "Graves'" in MCE Product Catalog:

3
Propylthiouracil
Propylthiouracil
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3 Cited Publications
Cat. No.: HY-B0346
CAS No.: 51-52-5
Synonyms: 6-n-Propylthiouracil; 6-Propyl-2-thiouracil; PTU
Target:  

Environmental Pollutants Thyroid Hormone Receptor

Research Areas:  

Endocrinology

Propylthiouracil (6-n-Propylthiouracil), a thioamide antithyroid agent, is an orally active thyroperoxidase and type-1 deiodinase (DIO1) inhibitor. Propylthiouracil can be used for the Graves disease and hyperthyroidism research .
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ML224
ML224
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1 Cited Publications
Cat. No.: HY-12381
CAS No.: 1338824-21-7
Purity:  99.18%
Synonyms: NCGC00242364; ANTAG3
Target:  

TSH Receptor

Research Areas:  

Endocrinology

ML224 (NCGC00242364) is a selective TSHR antagonist with an IC50 value of 2.1 µM. ML224 can be used in the study of Graves' disease and other thyroid disorders.
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Anti-TSHR Antibody (M22)
Anti-TSHR Antibody (M22)
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Cat. No.: HY-P991202

Target:  

TSH Receptor PKA

Research Areas:  

Cardiovascular Disease Inflammation/Immunology

Anti-TSHR Antibody (M22) is a selective agonist targeting TSHR (thyroid-stimulating hormone receptor), acting through competitive binding to the extracellular domain of TSHR. Anti-TSHR Antibody (M22) can mimic the biological effects of thyroid-stimulating hormone (TSH), activating downstream cAMP-PKA and other signaling pathways. Anti-TSHR Antibody (M22) can stimulate the proliferation of thyroid follicular epithelial cells and human umbilical vein endothelial cells (HUVECs), promote angiogenesis and tube formation, cell migration, and also upregulate the expression of angiogenesis-related proteins such as PROX1. Anti-TSHR Antibody (M22) can be used in research areas such as the mechanisms of goiter formation in Graves' disease (GD), angiogenesis regulation, and TSHR antagonist screening .
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Iscalimab (WT IgG1)
Iscalimab (WT IgG1)
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Cat. No.: HY-P99670
CAS No.: 2031153-61-2
Synonyms: CFZ-533 (WT IgG1); OM11-62MF (WT IgG1)
Target:  

TNF Receptor

Research Areas:  

Metabolic Disease Inflammation/Immunology

Iscalimab (WT IgG1) (CFZ-533 (WT IgG1)) is an IgG1 monoclonal antibody that retains a native wild-type Fc region and targets CD40. Iscalimab (WT IgG1) can be used in research concerning Graves' hyperthyroidism and autoimmune diseases .
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13Z,16Z-Docosadienoic acid
13Z,16Z-Docosadienoic acid
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Cat. No.: HY-114610
CAS No.: 17735-98-7
Purity:  99.00%
Category:  

Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Free Fatty Acid Receptor Bacterial

13Z,16Z-Docosadienoic acid is a GPR120 agonist with bactericidal activity. 13Z,16Z-Docosadienoic acid serves as a potential biomarker for canine mammary tumors. 13Z,16Z-Docosadienoic acid is used in the research of bacterial infections, Lyme disease, Graves' disease and mammary tumors .
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TSHR antagonist S37a
TSHR antagonist S37a
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Cat. No.: HY-129995A
CAS No.: 2143452-20-2
Purity:  98.00%
Target:  

TSH Receptor

Research Areas:  

Endocrinology

TSHR antagonist S37a is a highly selective thyrotropin receptor (TSHR) antagonist, with potential for the treatment of Graves' orbitopathy .
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Org 274179-0
Org 274179-0
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Cat. No.: HY-153213
CAS No.: 1421683-12-6
Target:  

TSH Receptor GnRH Receptor Phospholipase

Research Areas:  

Neurological Disease Inflammation/Immunology

Org 274179-0 is a low-molecular-weight allosteric thyrotropin receptor (TSH Receptor) antagonist with equipotent follicle-stimulating hormone receptor antagonistic activity and selectivity for the luteinizing hormone receptor. Org 274179-0 binds to the transmembrane domain of the thyrotropin receptor, stabilizes the receptor's inactive state, and blocks agonist-induced and constitutive signaling through the adenylyl cyclase/cAMP and phospholipase C pathways. Org 274179-0 can be used for research on Graves' disease and Graves' ophthalmopathy .
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NCGC00229600
NCGC00229600
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Cat. No.: HY-18286
CAS No.: 1338824-20-6
Target:  

TSH Receptor

Research Areas:  

Endocrinology

NCGC00229600 is an allosteric inverse agonist of thyrotropin receptor (TSHR). NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously expressed in Graves' disease .
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Progoitrin
Progoitrin
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Cat. No.: HY-N10348
CAS No.: 585-95-5
Category:  

Ketones, Aldehydes, Acids Glucosinolates Plants 500 - Internal Server Error | MedChemExpress

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