1 Result for "

HBP10

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HBP10" in MCE Product Catalog:

Cat. No.: HY-189745
Research Areas:  

Cancer

HBP-10 is an anticancer agent containing a Michael acceptor. HBP-10 induces intracellular ROS accumulation, triggering IRE1α-JNK/CHOP-mediated ER stress, γ-H2AX-positive DNA damage, and caspase-dependent apoptosis (apoptosis). HBP-10's above effects are attenuated by NAC (HY-B0215). HBP-10 exerts antiproliferative and cytotoxic effects on NSCLC cells and shows certain selectivity for NSCLC cells. HBP-10 can be used for research on EGFR-mutant non-small cell lung cancer .
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