9 Results for "

HMGA1

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "HMGA1" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N6800A
CAS No.: 18133-22-7
Netropsin dihydrochloride is a DNA minor groove binder (MGB) and antibiotic (antibiotic). Netropsin dihydrochloride exhibits antibacterial, antiparasitic, antiviral, and antitumor activities. Netropsin dihydrochloride binds with high affinity to the minor groove of A-T-rich DNA sequences, competitively blocking the binding of specific transcription factors (such as HMGA1) to target gene promoters or enhancers, thereby inhibiting chromatin loop formation and downstream gene transcription. Netropsin dihydrochloride is a Topoisomerase inhibitor that inhibits the catalytic activity of DNA Top I and II and impedes the stabilization of their DNA-protein cross-linking complexes. Netropsin dihydrochloride can be used in research on infections, cancer, and septicemia [1] .
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Cat. No.: HY-RS17912
Research Areas:  

Others

Hmga1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hmga1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS06230
Research Areas:  

Others

HMGA1 Human Pre-designed siRNA Set A contains three designed siRNAs for HMGA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS24381
Research Areas:  

Others

Hmga1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Hmga1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-N6800
CAS No.: 1438-30-8
Netropsin is a DNA minor groove binder (MGB) and antibiotic (antibiotic). Netropsin exhibits antibacterial, antiparasitic, antiviral, and antitumor activities. Netropsin binds with high affinity to the minor groove of A-T-rich DNA sequences, competitively blocking the binding of specific transcription factors (such as HMGA1) to target gene promoters or enhancers, thereby inhibiting chromatin loop formation and downstream gene transcription. Netropsin is a Topoisomerase inhibitor that inhibits the catalytic activity of DNA Top I and II and impedes the stabilization of their DNA-protein cross-linking complexes. Netropsin can be used in research on infections, cancer, and septicemia [1] .
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Cat. No.: HY-P81440
Synonyms: HMG R; HMG-I(Y); HMGA1; HMGA1A; HMGIY

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P81440A
Synonyms: HMG R; HMG-I(Y); HMGA1; HMGA1A; HMGIY

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P87965
Synonyms: HMGIY, HMGA1, High mobility group protein HMG-I/HMG-Y, HMG-I(Y), High mobility group AT-hook protein 1, High mobility group protein R, High mobility group protein A1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, FC

Reactivity:  

Human, Mouse

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Cat. No.: HY-184535
CAS No.: 3008320-14-4
PDIC-DPC is a HMGA1 inhibitor and lung-targeting agent. PDIC-DPC upregulates STING expression and enhances STING-mediated immune signaling. PDIC-DPC inhibits the TGFβ-Smad pathway and activates AMPK. PDIC-DPC forms nanocomplexes with fibrinogen β chain and vitronectin, and achieves lung-specific accumulation by binding to pulmonary endothelial receptors. PDIC-DPC reverses established pulmonary fibrosis, reduces collagen deposition, restores alveolar structure, improves pulmonary function, and inhibits in situ ESCC growth. PDIC-DPC can be used for the research of esophageal squamous cell carcinoma and idiopathic pulmonary fibrosis [1] .
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