174

174 Publications Verification

CAS No.: 20350-15-6

Synonyms: BFA; Cyanein; Decumbin

Category:

Infection Microorganisms Macrolide Antibiotics Antibiotics Antiviral Disease Research Anticancer Disease Research Fields

Target:

Autophagy Mitophagy HSV Antibiotic Bacterial

Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus . Brefeldin A is also an autophagy and mitophagy inhibitor . Brefeldin A inhibits HSV-1 and has anti-cancer activity .

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46

Salubrinal

46 Cited Publications

Cat. No.: HY-15486

CAS No.: 405060-95-9

Purity: 99.51%

Target:

Phosphatase HSV Autophagy Apoptosis

Research Areas:

Infection Inflammation/Immunology Cancer

Salubrinal is a cell-permeable and selective inhibitor of eIF2α dephosphorylation . Salubrinal acts as a dual-specificity phosphatase 2 (Dusp2) inhibitor and suppresses inflammation in anti-collagen antibody-induced arthritis . Salubrinal has antiviral activity against HSV-1 and inhibits dephosphorylation of eIF2α mediated by the HSV-1 protein ICP34.5 .

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33

Ganciclovir

33 Cited Publications

Cat. No.: HY-13637

CAS No.: 82410-32-0

Purity: 99.89%

Synonyms: BW 759; 2'-Nor-2'-deoxyguanosine

Target:

CMV HSV Antibiotic Nucleoside Antimetabolite/Analog

Research Areas:

Infection Cancer

Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC₅₀ of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain .

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33

Ganciclovir sodium

33 Cited Publications

Cat. No.: HY-13637A

CAS No.: 107910-75-8

Purity: 99.92%

Synonyms: BW 759 sodium; 2'-Nor-2'-deoxyguanosine sodium

Target:

CMV HSV Antibiotic Nucleoside Antimetabolite/Analog

Research Areas:

Infection Cancer

Ganciclovir (BW 759) sodium, a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir sodium also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir sodium inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir sodium has an IC₅₀ of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain .

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29

Acyclovir

29 Cited Publications

Cat. No.: HY-17422

CAS No.: 59277-89-3

Synonyms: Aciclovir; Acycloguanosine

Target:

HSV Apoptosis Antibiotic Bacterial

Research Areas:

Infection Cancer

Acyclovir (Aciclovir) is a potent, orally active antiviral agent. Acyclovir has antiherpetic activity with IC₅₀ values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir induces cell cycle perturbation and apoptosis. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia .

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29

Acyclovir sodium

29 Cited Publications

Cat. No.: HY-17422A

CAS No.: 69657-51-8

Synonyms: Aciclovir sodium; Acycloguanosine sodium

Target:

HSV Apoptosis Antibiotic Bacterial

Research Areas:

Infection Cancer

Acyclovir (Aciclovir) sodium is a potent, orally active antiviral agent. Acyclovir sodium has antiherpetic activity with IC₅₀ values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir sodium induces cell cycle perturbation and apoptosis. Acyclovir sodium prevents bacterial infections during induction therapy for acute leukaemia .

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23

Adenosine monophosphate

23 Cited Publications

Cat. No.: HY-A0181

CAS No.: 61-19-8

Synonyms: AMP

Category:

Microorganisms Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields

Target:

Endogenous Metabolite Adenosine Receptor HSV

Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

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23

Adenosine 5'-monophosphate monohydrate

23 Cited Publications

Cat. No.: HY-A0181A

CAS No.: 18422-05-4

Synonyms: 5'-AMP monohydrate

Category:

Ketones, Aldehydes, Acids Endogenous metabolite

Target:

Endogenous Metabolite Adenosine Receptor HSV

Adenosine 5'-monophosphate monohydrate is an adenosine A₁ receptor agonist. Adenosine 5'-monophosphate monohydrate has significant antiviral activity against HSV-1 and HSV-2 .

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