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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
HuR RNA binding
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "HuR RNA binding" in MCE Product Catalog:
2
2 Cited Publications
CMLD-2, an inhibitor of HuR-ARE interaction, competitively binds HuR protein disrupting its interaction with adenine-uridine rich elements (ARE)-containing mRNAs (Ki=350 nM). CMLD-2 induces apoptosis exhibits antitumor activity in different cancer cells as colon, pancreatic, thyroid and lung cancer cell lines. Hu antigen R (HuR) is an RNA binding protein, can regulate target mRNAs stability and translation .
1
1 Cited Publications
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value of 0.35 μM. KH-3 has anti-proliferative activity. KH-3 suppresses breast cancer cell invasion as well as delays the initiation of lung colonies by disrupting HuR-FOXQ1 mRNA interaction .
Cat. No.: HY-163759
CAS No.: 3040301-46-7
Target:
Research Areas:
HuR degrader 2 is a molecular glue degrader targeting HuR (ELAVL1). HuR degrader 2 degrades the RNA-binding protein HuR. HuR degrader 2 can be used for the research of pancreatic ductal adenocarcinoma .
Cat. No.: HY-124844
CAS No.: 1448460-87-4
Synonyms: AZA-9
Azaphilone-9 (AZA-9) is an inhibitor of HuR-ARE RNA interaction (IC50=1.2 μM) by binding RNA-binding protein Hu antigen R (HuR). The HuR-RNA interactions stabilize many oncogenic mRNAs in tumors. Thus Azaphilone-9 potentially inhibit cancer cell growth and progression .
Cat. No.: HY-101112
CAS No.: 137018-54-3
Category:
Target:
Cat. No.: HY-P702827
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ELAVL1; Embryonic Lethal, Abnormal Vision, Drosophila, Homolog-Like 1; Prev. HuR; Human Antigen R; HuR; Hu Antigen R; MelG; Hu-Antigen R; Hua; ELAV1; ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R); ELAV Like RNA binding Protein
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
