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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Hydrochlorothiazide
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Hydrochlorothiazide" in MCE Product Catalog:
8
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Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect .
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14 Publications Verification
Synonyms: HOE 140 acetate
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1
1 Cited Publications
Cat. No.: HY-P10579
CAS No.: 2225868-19-7
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Cat. No.: HY-P10303
CAS No.: 2767993-86-0
Synonyms: Cyclo[RGDfK(Azide)]
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Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] (Cyclo[RGDfK(Azide)]) is a derivative of Cyclo (-RGDfK) (HY-P0023). Cyclo[Arg-Gly-Asp-D-Phe-Lys (Azide)] is a click chemistry reagent containing an azide group. Cyclo[Arg-Gly-Asp-D-Phe-Lys (Azide)] enables functionalization of alginate via SPAAC bioconjugation. Alginate hydrogels functionalized with Cyclo[Arg-Gly-Asp-D-Phe-Lys (Azide)] significantly promote cell expansion while maintaining cell pluripotency .
Cat. No.: HY-B0252S1
CAS No.: 1190006-03-1
Synonyms: HCTZ-13C,d2
Research Areas:
Hydrochlorothiazide (Standard) is the analytical standard of Hydrochlorothiazide. This product is intended for research and analytical applications. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect .
Cat. No.: HY-B0252S
CAS No.: 1219798-89-6
Synonyms: HCTZ-d2
Cat. No.: HY-B0252S3
CAS No.: 2140316-81-8
Synonyms: HCTZ-15N2,13C,d2
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5-Chloro hydrochlorothiazide is a derivative of hydrochlorothiazide (HY-B0252), and has diuretic action .
Cat. No.: HY-Z8643
CAS No.: 402824-96-8
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HCTZ-CH2-HCTZ is an isomer of HCTZ (HY-B0252). Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway .
Cat. No.: HY-B0252S2
CAS No.: 1261396-79-5
Synonyms: HCTZ-13C6
Cat. No.: HY-144140S
Purity: 99.34%
Cat. No.: HY-W343043
CAS No.: 60398-24-5
Synonyms: PZG
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Pyrazinoylguanidine (PZG) is an analogue of the potassium sparing diuretic, Amiloride (HY-B0285). Pyrazinoylguanidine can lower the systolic and diastolic blood pressure of patients with primary hypertension, has a certain effect on reducing heart rate, and does not affect the concentrations of electrolytes such as sodium, potassium, and chloride in the blood serum. Pyrazinoylguanidine can reduce the hyperglycemia and hyperinsulinemia in type 2 diabetes, reduce the levels of triglycerides, cholesterol, and free fatty acids, and reverse the hyperglycemia and hyperlipidemia induced by thiazide diuretics, such as Hydrochlorothiazide (HY-B0252). Pyrazinoylguanidine ican nhibit the reabsorption of urea by the renal tubules, thereby increasing the clearance rate and excretion volume of urea, reducing the serum urea concentration, and minimizing its toxic accumulation .
Cat. No.: HY-182407
CAS No.: 100277-62-1
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CV 5975 is an orally active angiotensin converting enzyme (ACE) competitive inhibitor with a rabbit lung ACE IC50 of 3.1 nM and Ki values of 2.6 nM. CV 5975 inhibits ACE in plasma, aorta, kidney, and brain, intensifying inhibition with repeated administration. CV 5975 inhibits Angiotensin I (HY-P1032)-induced pressor responses and ileum contraction, and augments bradykinin-induced ileum contraction and depressor responses. CV 5975 reduces blood pressure via ACE-independent mechanisms, with sustained action across multiple hypertensive and normotensive animal models, intensified by repeated dosing or Hydrochlorothiazide (HY-B0252) co-administration. CV 5975 can be used for the research of hypertension .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
