2 Results for "

IACS9439

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "IACS9439" in MCE Product Catalog:

Cat. No.: HY-153243
CAS No.: 2231259-36-0
Target:  

c-Fms

Research Areas:  

Cancer

IACS-9439 is a potent, selective, and orally active CSF1R inhibitor with a Ki value of 1 nM inhibitor. IACS-9439 can be used for advanced solid tumors research .
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Cat. No.: HY-187646
CAS No.: 2231259-57-5
Target:  

Drug Derivative

Research Areas:  

Cancer

IACS-9439-Cl is a derivative of IACS-9439. IACS-9439 is an orally active and selective colony-stimulating factor 1 receptor (CSF1R) inhibitor with a Kd of 1 nM. IACS-9439-Cl reduces the population of tumor-associated macrophages. IACS-9439-Cl promotes the polarization of macrophages toward the M1 anti-tumor phenotype and decreases the M2 pro-tumor phenotype, thereby exerting a tumor growth inhibitory effect. IACS-9439-Cl can be used in cancer-related research .
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