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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
IDG16177
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "IDG16177" in MCE Product Catalog:
Cat. No.: HY-147420
CAS No.: 2230597-99-4
Synonyms: IDG-16177
Research Areas:
Xelaglifam is an orally active GPR40/FFAR1 agonist and PPARγ coactivator recruitment inhibitor (IC50 74.7 µM). Xelaglifam activates Gq/IP3/Ca 2+ and β-arrestin, stimulates glucose-dependent insulin secretion from pancreatic β cells, improves glucose tolerance, reduces fasting hyperglycemia, protects pancreatic β cells, inhibits DP1, BSEP (IC50 14.3 µM), MRP2 (39.9 µM) and MRP4 (4.4 µM), activates FXR, regulates bile acid homeostasis, and modulates mitochondrial function, membrane potential and cellular ATP. Xelaglifam can be used for research on type 2 diabetes .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
