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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
KUS187
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "KUS187" in MCE Product Catalog:
Cat. No.: HY-134499
CAS No.: 1357164-95-4
Research Areas:
KUS187 is an orally active VCP ATPase modulator that inhibits VCP ATPase activity and reduces cellular ATP consumption. KUS187 prevents MPP +, low Glucose (D-Glucose) (HY-B0389)-, and Tunicamycin (HY-A0098)-induced cytoplasmic and mitochondrial ATP depletion. KUS187 inhibits ER stress, suppresses AMPK activation, prevents loss of mitochondrial membrane potential and changes in mitophagy, and protects neurons from MPP +-induced death/neurite retraction. KUS187 can be used for research on Parkinson's disease, retinitis pigmentosa, and retinal ganglion cell injury .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
