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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
LDL-oxidation
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "LDL-oxidation" in MCE Product Catalog:
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2 Cited Publications
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N-Acetyl lysyltyrosylcysteine amide is a potent, reversible, specific, and non-toxic tripeptide inhibitor of myeloperoxidase (MPO). N-Acetyl lysyltyrosylcysteine amide effectively inhibits MPO generation of toxic oxidants in vivo. N-Acetyl lysyltyrosylcysteine amide reduces neuronal damage and preserves brain tissue and neurological function in the stroked brain. N-Acetyl lysyltyrosylcysteine amide inhibits MPO-dependent hypochlorous acid (HOCl) generation, protein nitration, and LDL oxidation .
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Plant Monophenols Metabolic Disease Phenols Other Families Extract Microorganism Endogenous metabolite Disease Research Fields
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1
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Flavonols Plant Flavonoids Pedaliaceae Extract Uncarina grandidieri (Baill.) Ihlenf. & Straka Extract
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Convolvulaceae Extract Plant Ipomoea batatas (Linn.) Lamarck Extract Simple Phenylpropanols Phenols Polyphenols Phenylpropanoids
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Cat. No.: HY-N0859
CAS No.: 69363-14-0
Synonyms: Schizanhenol; Gomisin-K3
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Plant Monophenols Lignans Schisandra chinensis (Turcz.) Baill. Extract Phenols Phenylpropanoids Schisandraceae Extract Disease Research Fields Cancer
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LDL-IN-2 (compound 3) is an antioxidant against copper mediated low-density lipoproteins (LDL) oxidation .
Cat. No.: HY-N3596
CAS No.: 84575-10-0
Synonyms: Aquillochin
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Thymelaeaceae Extract Plant Phenols Polyphenols Aquilaria sinensis (Lour.) Spreng. Extract
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Cat. No.: HY-N10638
CAS No.: 916888-49-8
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N-Acetyldopamine dimer-2 (compound 2) is a N-acetyldopamine dimer that can be isolated from the yellow powder form Periostracum Cicadae with antioxidant and anti-inflammatory activities. N-Acetyldopamine dimer-2 inhibits oxidized low-density lipoprotein (LDL) oxidation, ROS generation, NO production, and NF-κB activity .
Cat. No.: HY-N15706
CAS No.: 76939-42-9
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Cat. No.: HY-N0339S
CAS No.: 84759-06-8
Cat. No.: HY-119265
CAS No.: 615264-62-5
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LDL-IN-4 (Compound 2) inhibits human acyl-CoA:cholesterol acyltransferase-1 and -2 activities. LDL-IN-4 inhibits copper-mediated low density lipoprotein (LDL) oxidation, with an IC50 of 3 μM. LDL-IN-4 has anti-atherosclerotic biological activity .
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LDL-IN-1 (Compound 1) is an antioxidant, and is active against copper mediated LDL oxidation (IC50 = 52 μM). LDL-IN-1 is also an Acyl-CoA:cholesterol acyltransferase-1 and -2 (ACAT-1/2) inhibitor, with IC50s of 60 μM. LDL-IN-1 can be used for anti-atherosclerotic research .
Cat. No.: HY-113269R
CAS No.: 4072-32-6
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Cat. No.: HY-W778608R
CAS No.: 38934-20-2
Synonyms: Quercetin 7-O-β-glucuronide (Standard)
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Flavonols Plant Flavonoids Pedaliaceae Extract Uncarina grandidieri (Baill.) Ihlenf. & Straka Extract
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Cat. No.: HY-137390A
CAS No.: 1009811-63-5
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(3S,5R)-Fluvastatin (potassium) is a synthetic hypolipidemic drug that inhibits HMG-CoA reductase activity. (3S,5R)-Fluvastatin (potassium) has similar antioxidative effects on copper ion-induced LDL oxidation compared to its 3R,5S enantiomer. (3S,5R)-Fluvastatin (potassium) and its metabolites demonstrate a potential to exhibit anti-atherosclerotic effects through their antioxidative activities. (3S,5R)-Fluvastatin (potassium) is clinically utilized as part of a racemic mixture for reducing plasma cholesterol levels.
Cat. No.: HY-N0859R
CAS No.: 69363-14-0
Synonyms: Schizanhenol (Standard); Gomisin-K3 (Standard)
Cat. No.: HY-106621A
CAS No.: 158513-06-5
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AL 0671 is a potassium channel opener. AL 0671 can inhibit nonenzymatic glycation of protein and LDL oxidation. AL 0671 can be used for the researches of cardiovascular and metabolic disease, such as hypertensive diabetes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
