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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
LFA-1 integrin
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "LFA-1 integrin" in MCE Product Catalog:
12
Target:
Research Areas:
Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease .
12
12 Cited Publications
Cat. No.: HY-19344A
CAS No.: 1119276-80-0
Synonyms: SAR 1118 sodium; SHP-606 sodium
Target:
Research Areas:
Lifitegrast (SAR 1118) sodium is a potent integrin antagonist. Lifitegrast sodium blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast sodium inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast sodium can be used for researching dry eye disease .
Cat. No.: HY-P990835
Target:
Research Areas:
Cat. No.: HY-19344R
CAS No.: 1025967-78-5
Synonyms: SAR 1118 (Standard); SHP-606 (Standard)
Target:
Research Areas:
Lifitegrast (Standard) is the analytical standard of Lifitegrast. This product is intended for research and analytical applications. Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease .
Cat. No.: HY-19344S2
Cat. No.: HY-P990871
Target:
Research Areas:
Cat. No.: HY-150181
CAS No.: 1609659-32-6
Target:
Research Areas:
IBE-667 is a LFA-1 integrin agonist with a Kd value of 52 nM. IBE-667 increases the stability of the open conformation of LFA-1 and enhances its affinity for ICAM-1. IBE-667 can be used in studies related to leukocyte adhesion deficiency .
Cat. No.: HY-19344S
Synonyms: SAR 1118-d4; SHP-606-d4
Cat. No.: HY-19344S1
CAS No.: 2249814-79-5
Synonyms: SAR 1118-d6; SHP-606-d6
Cat. No.: HY-P704217
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGAL; integrin Alpha-L; Prev. CD11A; HNA-5; LFA-1; Antigen CD11A (P180), Lymphocyte Function-Associated Antigen 1, Alpha Polypeptide; LFA1A; CDNA FLJ57691, Highly Similar To integrin Alpha-L; integrin, Alpha L (Antigen CD11A (P180), Lymphocyte Function-A
Species:
Human
Source:
CHO
Cat. No.: HY-P700758
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGAL; integrin Alpha-L; Prev. CD11A; HNA-5; LFA-1; Antigen CD11A (P180), Lymphocyte Function-Associated Antigen 1, Alpha Polypeptide; LFA1A; CDNA FLJ57691, Highly Similar To integrin Alpha-L; integrin, Alpha L (Antigen CD11A (P180), Lymphocyte Function-A
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P705545
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ITGAD; Leukointegrin Alpha D; integrin Subunit Alpha D; integrin Alpha-D; ADB2; Beta-2 integrin AlphaD Subunit; CD11d; integrin, Alpha D; CD11 Antigen-Like Family Member D; CD11d Antigen; ITGB2; Cell Surface Adhesion Glycoproteins LFA-1/CR3/P150,95 Subuni
Species:
Human
Source:
CHO
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
