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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
LRK4189
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "LRK4189" in MCE Product Catalog:
Cat. No.: HY-175751
CAS No.: 3063346-83-5
LRK-4189 is an orally active CRBN-dependent PIP4K2C PROTAC degrader. LRK-4189-mediated degradation of PIP4K2C leads to intrinsic cell death and upregulation of the STAT1 pathway and signaling in microsatellite stable colorectal cancer (MSS CRC) cells. LRK-4189 can be used for the research of microsatellite-stable colorectal cancer .
Cat. No.: HY-175751A
CAS No.: 3063345-48-9
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(Rac)-LRK-4189 is the racemate of LRK-4189 (HY-175751).
Cat. No.: HY-189439
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E3 ligase Ligand 86 is a CRBN E3 ligase ligand that can be used in the synthesis of PROTACs, such as LRK-4189 (HY-175751) .
Cat. No.: HY-189438
Research Areas:
PIP4K ligand-1 is the target protein ligand for the molecular glue LRK-4189 (HY-175751) and can be used in research on microsatellite-stable colorectal cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
