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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
LYPLA1
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "LYPLA1" in MCE Product Catalog:
12
Target:
Research Areas:
ML348 (GNF-Pf-1127) is a selective and reversible acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) inhibitor with an IC50 of 210 nM, and barely inhibits LYPLA2 [1].
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ML-211 is a potent dual inhibitor of LYPLA1 and LYPLA2 enzymes, with an IC50 value of 17 nM against LYPLA1, 30 nM against LYPLA2, and 10 nM against ABHD11 [1].
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ML226 is a potent inhibitor of α/β hydrolase domain protein 11 (ABHD11), with in vitro and in situ IC50 values of 15 and 0.68 nM, respectively. ML226 is an inhibitor of protein palmitoylthioesterase lysophospholipase 1 (LYPLA1) and LYPLA2. ML226 can be used for research related to neurological diseases [1].
Cat. No.: HY-RS07921
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LYPLA1 Human Pre-designed siRNA Set A contains three designed siRNAs for LYPLA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24321
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Lypla1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lypla1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17852
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Research Areas:
Lypla1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lypla1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-120126
CAS No.: 1831135-21-7
Synonyms: CID71710938; JJH-254
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Research Areas:
ML378 (CID71710938) is a dual LYPLA1 and LYPLA2 inhibitor, with IC50s of 122 nM and 245 nM respectively. ML378 also shows potent inhibition of ABHD6 (IC50 = 3.15 nM). ML378 can be used for elucidating the patho/physiological roles of the LYPLA1 and LYPLA2 [1].
Cat. No.: HY-P7539
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LYPLA1; Palmitoyl-Protein Hydrolase; Lysophospholipase 1; APT1; Acyl-Protein Thioesterase 1; LysoPLA I; Lysophospholipase I; LPL-I; APT-1; HAPT1; LPL1; Lysophospholipid-Specific Lysophospholipase
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
