6 Results for "

MES-SA

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "MES-SA" in MCE Product Catalog:

Cat. No.: HY-W035709
CAS No.: 485-65-4
Synonyms: Dihydrocinchonine
Hydrocinchonine (Dihydrocinchonine) is a multidrug resistance (MDR)-reversal agent. Hydrocinchonine directly inhibits the function and expression of P-gp, which is the mechanism by which it reverses MDR. Hydrocinchonine exerts synergistic apoptotic effect with Paclitaxel (HY-B0015) in MES-SA/DX5 cells. Hydrocinchonine can be used for the study of gynecological malignant tumors (such as uterine sarcoma) with drug resistance caused by excessive expression of P-gp .
loading...
    loading...
Cat. No.: HY-121255
CAS No.: 482-22-4
Purity:  ≥99.0%
Synonyms: (R)-Cryptopleurine; NSC 19912
Target:  

TMV

Research Areas:  

Cancer

(–)-Cryptopleurine is an alkaloid that has been found in Lauraceae and has diverse biological activities. It inhibits the growth of human A375 melanoma, A431 epidermoid carcinoma, A549 lung, MES-SA uterine sarcoma, and MCF-7 breast cancer cells (IC50=3 nM for all).2 (–)-Cryptopleurine inhibits hypoxia-induced gene expression in a hypoxia response element (HRE) reporter assay (IC50=8.7 nM).3 (–)-Cryptopleurine (500 μg/mL) prevents lesion formation in tobacco (N. tabacum) plants infected with tobacco mosaic virus (TMV). It also inhibits protein synthesis by yeast and mammalian ribosomes.
loading...
    loading...
Cat. No.: HY-W035709R
CAS No.: 485-65-4
Synonyms: Dihydrocinchonine (Standard)
Hydrocinchonine (Dihydrocinchonine) (Standard) is the analytical standard of Hydrocinchonine (HY-W035709). This product is used for research and analytical purposes.Hydrocinchonine is a multidrug resistance (MDR)-reversal agent. Hydrocinchonine directly inhibits the function and expression of P-gp, which is the mechanism by which it reverses MDR. Hydrocinchonine exerts synergistic apoptotic effect with Paclitaxel (HY-B0015) in MES-SA/DX5 cells. Hydrocinchonine can be used for the study of gynecological malignant tumors (such as uterine sarcoma) with drug resistance caused by excessive expression of P-gp .
loading...
    loading...
Cat. No.: HY-144872
CAS No.: 1170694-29-7
Target:  

Drug Derivative

Research Areas:  

Cancer

RJ-34, an aristolactam analogue, exhibits potent antitumor activities against a broad array of cancer cell lines with GI50 values in the subnanomolar range (GI50 <0.1 nM for A431, MES-SA, MES-SA/DX5, HCT-15, and HCT-15/CLO2 cells) .
loading...
    loading...
Cat. No.: HY-163664
CAS No.: 3040385-73-4
Target:  

Microtubule/Tubulin

Research Areas:  

Cancer

Tubulin polymerization-IN-63 (compound 6) is a tubulin polymerization inhibitor. The IC50 value of Tubulin polymerization-IN-63 for MES-SA cells is 0.29 μM. Tubulin polymerization-IN-63 can be used in cancer research .
loading...
    loading...
Cat. No.: HY-N13192
CAS No.: 7578-68-9
Target:  

Others

3-Acetoxyflavone shows antiproliferative activities against LoVo, LoVo/DX and MES-SA cell lines (IC50 from 4.7 μM to 7.8 μM, respectively), which is promising for research of cancers .
loading...
    loading...