Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
MKT077
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "MKT077" in MCE Product Catalog:
18
18 Publications Verification
Synonyms: FJ-776
1
1 Cited Publications
Cat. No.: HY-18399
CAS No.: 409086-68-6
Target:
Research Areas:
YM-1 is a stable MKT-077 (HY-15096) analog and an orally active Hsp70 inhibitor. YM-1 induces cell death of HeLa cells and up-regulates the level of p53 and p21 proteins .
Cat. No.: HY-18406
CAS No.: 1427450-47-2
YM-1 tosylate is a stable MKT-077 (HY-15096) analog and an orally active Hsp70 inhibitor. YM-1 tosylate induces cell death of HeLa cells and up-regulates the level of p53 and p21 proteins .
Cat. No.: HY-189882
Target:
Research Areas:
MKT-077-NH2 TFA is a MKT-077 (HY-15096) derivative bearing an aminoethylpyridinium substituent. MKT-077-NH2 TFA serves as an intermediate for organic synthesis-related research, such as acting as the Hsc70 ligand of Hsc70TAC BRD4 degrader-1 (HY-189881) .
Cat. No.: HY-189881
Research Areas:
Hsc70TAC BET Degrader-1 is a selective BET Hsc70TAC degrader. Hsc70TAC BET Degrader-1 recruits Hsc70 and directs BRD4 and BRD2 into lysosomes for chaperone-mediated Autophagy degradation. Hsc70TAC BET degrader-1 induces Apoptosis and downregulates c-Myc. Hsc70TAC BET degrader-1 can be used for leukemia research (BET ligand: JQ-1 carboxylic acid (HY-78695); Hsc70 ligand: MKT-077-NH2 TFA (HY-189882); Linker: 8-Aminooctanoic acid (HY-W018678)) .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
