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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
MV14
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "MV14" in MCE Product Catalog:
Cat. No.: HY-190489
CAS No.: 2377778-85-1
MV14 is a small-molecule NO donor that exhibits selective antiproliferative activity against bladder cancer cells. MV14 releases NO, causing DNA double-strand damage, inhibiting the NF‑κB pathway, and downregulating the apoptosis-inhibitory protein Survivin. MV14 interferes with the cell cycle and promotes tumor cell apoptosis. MV14 attenuates tumor-associated histopathological changes, urothelial destruction, and stromal invasion in the BBN (HY-W755252)-induced mouse bladder cancer model, and reduces PCNA levels in bladder tumor tissue while increasing active caspase-3. MV14 can be used for research on bladder cancer .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
