5 Results for "

Magnolignan A

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Magnolignan A" in MCE Product Catalog:

loading...
    loading...
Cat. No.: HY-116637
CAS No.: 20601-85-8
Purity:  99.79%
Synonyms: Magnolignan
Tetrahydromagnolol (Magnolignan), the main metabolite of Magnolol, is a potent and selective cannabinoidCB2 receptor agonist (EC50 =170 nM) and GPR55 antagonist. The Ki of Tetrahydromagnolol for CB2 is 416 nM, 20-fold higher than for the CB1 receptor. Magnolol shows antifungal, anti-inflammatory and analgesic effects .
loading...
    loading...
Cat. No.: HY-N15522
CAS No.: 2883117-61-9
Bi-magnolignan is a novel orally active bisbenzofuran lignan natural product with anticancer activity. Bi-magnolignan indirectly activates TBK1, triggering mitophagy, while binding to BRD4 (Kd 9.80 μM) to inhibit bromodomain transcriptional function. Bi-magnolignan disrupts the G2/M DNA damage checkpoint, inhibits homologous recombination repair, and induces DNA double-strand breaks and tumor cell apoptosis. Bi-magnolignan inhibits the growth of HCT116 and 4T1 xenograft tumors . Bi-magnolignan can be used for research related to triple-negative breast cancer and colorectal cancer .
loading...
    loading...
loading...
    loading...
Cat. No.: HY-N15712
CAS No.: 138591-13-6
Magnolignan I is a phenolic compound and a dilignan, which can be isolated from Magnoliae Cortex produced in China .
loading...
    loading...