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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Mereletinib
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Mereletinib" in MCE Product Catalog:
214
214 Publications Verification
Synonyms: AZD-9291; Mereletinib
Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer .
214
214 Publications Verification
Synonyms: AZD-9291 mesylate; Mereletinib mesylate
Osimertinib mesylate (AZD9291 mesylate) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer .
214
214 Publications Verification
Cat. No.: HY-79077
CAS No.: 2070014-82-1
Synonyms: AZD-9291 dimesylate; Mereletinib dimesylate
Osimertinib dimesylate (AZD-9291 dimesylate) is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFR L858R and EGFR L858R/T790M, respectively.
Cat. No.: HY-15772R
CAS No.: 1421373-65-0
Synonyms: AZD-9291 (Standard); Mereletinib (Standard)
Target:
Research Areas:
Osimertinib (Standard) is the analytical standard of Osimertinib. This product is intended for research and analytical applications. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer .
Cat. No.: HY-15772S1
CAS No.: 2254100-49-5
Synonyms: AZD-9291-13C,d3; Mereletinib-13C,d3
Synonyms: AZD-9291-d6; Mereletinib-d6
Cat. No.: HY-15772AR
CAS No.: 1421373-66-1
Synonyms: AZD-9291 mesylate (Standard); Mereletinib mesylate (Standard)
Target:
Research Areas:
Osimertinib (mesylate) (Standard) is the analytical standard of Osimertinib (mesylate). This product is intended for research and analytical applications. Osimertinib mesylate (AZD9291 mesylate) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer .
Synonyms: Osimertinib-d5 mesylate; AZD-9291-d5 mesylate; Mereletinib-d5 mesylate
Dosimertinib mesylate is a potent and orally active EGFR inhibitor. Dosimertinib mesylate decreases the expression of p-EGFR and p-ERK protein levels. Dosimertinib mesylate shows antiproliferative and anti-tumor activity. Dosimertinib mesylate has the potential for the research of non-small-cell lung cancer (NSCLC) .
Cat. No.: HY-142283
CAS No.: 2403760-70-1
Synonyms: Osimertinib-d5; AZD-9291-d5; Mereletinib-d5
Target:
Research Areas:
Dosimertinib is a potent and orally active EGFR inhibitor. Dosimertinib decreases the expression of p-EGFR and p-ERK protein levels. Dosimertinib shows antiproliferative and anti-tumor activity. Dosimertinib has the potential for the research of non-small-cell lung cancer (NSCLC) .
Cat. No.: HY-79077R
CAS No.: 2070014-82-1
Synonyms: AZD-9291 dimesylate (Standard); Mereletinib dimesylate (Standard)
Target:
Research Areas:
Osimertinib (dimesylate) (Standard) is the analytical standard of Osimertinib (dimesylate). This product is intended for research and analytical applications. Osimertinib dimesylate (AZD-9291 dimesylate) is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R/T790M, respectively.
Cat. No.: HY-142283BS
CAS No.: 2719691-00-4
Synonyms: N-Desmethyl Osimertinib-d5; N-Desmethyl AZD-9291-d5; N-Desmethyl Mereletinib-d5
N-Desmethyl dosimertinib is the deuterium labeled N-Desmethyl dosimertinib.
Cat. No.: HY-142283CS
CAS No.: 2719690-98-7
Synonyms: N-Methyl-Osimertinib-d5; N-Methyl-AZD-9291-d5; N-Methyl-Mereletinib-d5
N-Methyl-dosimertinib is the deuterium labeled of N-Methyl-osimertinib.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
