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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
NIR-II imaging
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "NIR-II imaging" in MCE Product Catalog:
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1 Cited Publications
Cat. No.: HY-133852
CAS No.: 1151666-58-8
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1 Cited Publications
Cat. No.: HY-D1464
CAS No.: 1622250-38-7
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1 Cited Publications
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FD-1080 free acid is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 free acid can be used for in vivo imaging .
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Cat. No.: HY-D1450
CAS No.: 155613-98-2
Synonyms: S01448
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IR-1048 is a nitroreductase (NTR)-responsive near-infrared fluorescence (NIR)/photoacoustic (PA) imaging probe and photothermal agent. IR-1048 is coupled with a nitroimidazole group to form IR-1048-MZ. IR-1048-MZ is catalytically reduced by NTR in a hypoxic environment, restoring strong near-infrared absorption and fluorescence emission (NIR II window), while activating the photothermal effect. IR-1048 relies on NTR-mediated electron transfer to relieve intramolecular fluorescence quenching, achieving specific imaging and photothermal ablation of tumor hypoxic areas. IR-1048 is mainly used for high-contrast NIR II/photoacoustic imaging and photothermal therapy research and tumor diagnosis of the tumor hypoxic microenvironment .
Cat. No.: HY-113553
CAS No.: 102185-28-4
Synonyms: (p-Aminophenyl)phosphocholine; p-Aminophenylphosphorylcholine; 4-APPC
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4-Aminophenylphosphorylcholine ((p-Aminophenyl) phosphocholine; p-Aminophenylphosphorylcholine; 4-APPC) is a phosphatidylcholine derivative that serves as a coupling ligand and antigen probe. When conjugated with gold nanoclusters, the phosphocholine head epitope of 4-Aminophenylphosphorylcholine is specifically recognized by anti-Pc IgM and CRP. It can be covalently coupled to human serum albumin (HSA) or glutathione-protected gold nanoclusters (Au-GSH) via covalent chemistry, respectively. The 4-Aminophenylphosphorylcholine-HSA complex acts as an ELISA coating antigen for detecting endogenous anti-Pc IgM antibodies in plasma; 4-Aminophenylphosphorylcholine-modified Au-GSH can be used to construct an ultra-stealthy NIR-II fluorescent gold nanocluster probe for imaging-related studies in mouse breast cancer and colon cancer models .
Cat. No.: HY-149298
CAS No.: 2946600-14-0
PSMA-IN-2 is an inhibitor of PSMA with a Ki value of 1.07 nM. PSMA-IN-2 displays favorable in vivo NIR imaging (λEM = 1088 nm, λex = 808 nm), and can be used for NIRII image-guided tumor resection surgery in PSMA-positive tumor-bearing mice .
Cat. No.: HY-149765
CAS No.: 2481214-36-0
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Bone-1064 is a EuK-based PSMA tetramer bone probe for high-contrast visualization of bone in surrounding tissue. Bone-1064 specifically binds hydroxyapatite in bone tissue and can be used for NIR-II fluorescence imaging in animal models .
Cat. No.: HY-D1381
CAS No.: 1988753-67-8
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CH1055-PEG is a water-soluble PEG-modified second near-infrared (NIR-II) small-molecule fluorescent dye. CH1055-PEG can be used in studies such as in vivo fluorescence imaging, tumor-targeted tracing, lymph node imaging, and image-guided surgery (λAbs/λem : 750/1055 nm) .
Cat. No.: HY-D3408
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STB-2 is a fluorescent dye for near-infrared window II (NIR-II) fluorescence angiography. STB-2 achieves high-brightness NIR-II fluorescence by restricting the twisted intramolecular charge transfer state. STB-2, when modified with ApoE to form nanoparticles, can cross the blood-brain barrier and accumulate in gliomas (Ex/Em = 808/1020 nm). STB-2 is used in studies related to NIR-II fluorescence and single-/two-photon cerebrovascular imaging of gliomas .
Cat. No.: HY-D3428
CAS No.: 2863678-02-6
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Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
LJ-2P is an NIR-II small-molecule fluorescent probe with fibrin/fibrinogen affinity. LJ-2P can bind coagulation-related proteins and restrict dye molecular motion, thereby enhancing local fluorescence for high-contrast imaging of bleeding and blood clots in vivo. LJ-2P can also co-precipitate with Ca 2+ to form LJ-2P nanoparticles, significantly enhancing NIR-II luminescence through the precipitation-enhanced emission (PEE) mechanism. LJ-2P can be used for research on bleeding disorders and breast cancer. LJ-2P exhibits dual-modal emission properties (Ex/Em ≈740/945 nm or 740/1066 nm) .
Cat. No.: HY-D3136
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MC-PSE is a fluorescent probe that can be used for glutathione (GSH) detection, NIR-II fluorescence imaging and ratiometric photoacoustic imaging. MC-PSE spontaneously forms J-aggregates in aqueous solution through π-π stacking, and its phenylselenyl group acts as a fluorescence quencher and GSH recognition receptor, thereby eliminating intrinsic fluorescence and generating a maximum absorption peak at 1000 nm. The excitation/emission wavelengths of MC-PSE are Ex = 808 nm and Em = 940 nm. MC-PSE can be applied in tumor-related research .
Cat. No.: HY-D3159
CAS No.: 2304942-78-5
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BTC1070 is an anti-quenching pentamethine cyanine NIR-II fluorescent probe. BTC1070 exhibits high brightness and excellent photostability in aqueous solution (Ex/Em = 1015/1065 nm). BTC1070 can clearly visualize lymphatic structures after intradermal injection, and produces a ratiometric fluorescence response in the acidic range to non-invasively quantify gastric pH. BTC1070 is applicable to studies related to in vivo deep tissue imaging and gastric pH sensing .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
