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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
NSC852426
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "NSC852426" in MCE Product Catalog:
Cat. No.: HY-189697
NSC 852426 is a PDGFRα/VEGFR-2 inhibitor with IC50 values of 1.179 μM and 1.818 μM, respectively. NSC 852426 inhibits AKT and ERK1/2 phosphorylation, upregulates P53, BAX, and caspase-3 while inhibiting Bcl-2, and induces intrinsic mitochondrial apoptosis. NSC 852426 exhibits selective antiproliferative and cytotoxic effects against multiple cancer cell lines, and shows moderate selectivity for leukemia and colon cancer subgroups. NSC 852426 can be used in cancer-related research, such as leukemia and colon cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
