71 Results for "

P60

" in MedChemExpress (MCE) Product Catalog:
Products (71)

71 Results for "P60" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-16558
CAS No.: 487-52-5
Synonyms: 2’,3,4,4’-tetrahydroxy Chalcone
Butein is a cAMP-specific PDE inhibitor with an IC50 of 10.4 μM for PDE4 . Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 μM for EGFR and p60 c-src in HepG2 cells . Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a . Butein is a SIRT1 activator (STAC).
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2
2 Cited Publications
Cat. No.: HY-P80899
Synonyms: P60; p62; A170; DMRV; OSIL; PDB3; ZIP3; p62B; NADGP; FTDALS3

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF, IP

Reactivity:  

Human

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1
1 Cited Publications
Cat. No.: HY-P1684
CAS No.: 1319725-20-6
Synonyms: FOXP3 inhibitor P60
Peptide P60 is a FOXP3 inhibitor. Peptide P60 reduces the nuclear translocation of FOXP3 and impairs FOXP3-mediated inhibition of NF-κB and NFAT activity. Peptide P60 inhibits the immunosuppressive activity of regulatory T cells and restores the proliferation and activation of effector T cells. Peptide P60 induces lymphoproliferative autoimmune syndrome in neonatal ICR mice and reduces the number of CD4 +CD25 +Foxp3 + T cells in the spleen. Peptide P60 enhances the efficacy of AH1 (HY-P4193) peptide vaccine and recombinant adenovirus-based HCV NS3 vaccine in BALB/c mice, including protective effects against CT26 tumor implantation. Peptide P60 can be used in studies related to tumor immunity, viral infection and lymphoproliferative autoimmune syndrome .
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1
1 Cited Publications
Cat. No.: HY-P80518
Synonyms: ORCA, OSIL, SQSTM1, Sequestosome-1, EBI3-associated protein of 60 kDa, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Ubiquitin-binding protein p62, EBIAP, P60, p62

Host:  

Mouse

Application:  

IHC-P, FC

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-P73916
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: HSPD1; HuCHA60; Prev. SPG13; CPN60; HSP60; Spastic Paraplegia 13 (Autosomal Dominant); 60 KDa Heat Shock Protein, Mitochondrial; Epididymis Secretory Sperm Binding Protein; Mitochondrial Matrix Protein P1; Heat Shock 60kD Protein 1 (Chaperonin); 60 KDa Chaperonin; Heat Shock 60kDa Protein 1 Isoform 2; Chaperonin 60; Heat Shock 60kDa Protein 1 Isoform 4; GroEL; Short Heat Shock Protein 60 HsP60s1; Heat Shock 60kDa Protein 1 (Chaperonin); Heat Shock Protein 65; Heat Shock Protein Family D Member 1; HSP65; P60 Lymphocyte Protein; HsP60; Heat Shock Protein 60; HLD4; Heat Shock Protein Family D (HsP60) Member 1; HSP-60
Species:  
Mouse
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P80514
Synonyms: SRC1, SRC, Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene c-Src, pP60c-src, P60-Src

Host:  

Rabbit

Application:  

WB, FC

Reactivity:  

Human

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1
1 Cited Publications
Cat. No.: HY-P701321
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SRC; Tyrosine Kinase PP60c-Src; Prev. SRC1; P60-Src; C-Src; Protooncogene SRC, Rous Sarcoma; ASV; Tyrosine-Protein Kinase SRC-1; V-Src Avian Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog; PP60c-Src; Proto-Oncogene Tyrosine-Protein Kinase Src; THC6; SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase; Proto-Oncogene C-Src
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-162943
Research Areas:  

Cancer

P60-L3-VHL is a PROTAC degrader targeting Foxp3. P60-L3-VHL triggers the ubiquitination modification of Foxp3 by conjugating the Foxp3-targeting peptide P60 with the VHL E3 ubiquitin ligase ligand via a long linker, and mediates protein degradation through the proteasome pathway. P60-L3-VHL blocks the nuclear translocation of Foxp3, relieves the transcriptional inhibition of IL2 and IFN-γ, and inhibits the differentiation of iTreg cells. P60-L3-VHL is applicable to cancer-related research .
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Cat. No.: HY-162946
Research Areas:  

Cancer

Alkyne-P60 is a potent 15-mer peptide inhibitor of Foxp3. Alkyne-P60 can bind with Foxp3, hinder its nuclear translocation, and diminish Foxp3-mediated inhibition of NFKB and NFAT functions. Alkyne-P60 is a ligand for target protein for PROTAC (HY-162943).
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Cat. No.: HY-P10296
CAS No.: 153147-67-2
Target:  

Endogenous Metabolite

Research Areas:  

Infection

p60 (217–225) is the subdominant epitope of Listeria monocytogenes, which combines with H-2K d MHC class I molecules .
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Cat. No.: HY-162947
CAS No.: 3036674-82-2
Target:  

PROTAC Linkers

Research Areas:  

Cancer

2-(2-(2-(6-Azidohexanamido)ethoxy)ethoxy)acetic acid is a PROTACT linker and can be used for synthesis of P60-L3-VHL (HY-162943). 2-(2-(2-(6-Azidohexanamido)ethoxy)ethoxy)acetic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
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Cat. No.: HY-RS13745
Research Areas:  

Others

SQSTM1 Human Pre-designed siRNA Set A contains three designed siRNAs for SQSTM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P3743
CAS No.: 165190-42-1
Research Areas:  

Others

p60c-src Substrate is an efficient and specific substrate for p60c-src protein tyrosine kinase (PTK). p60c-src Substrate can be used to synthesize chimeric branched peptides .
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Cat. No.: HY-P3773
CAS No.: 168781-78-0
Target:  

Src

Research Areas:  

Cancer

p60c-src substrate II is an efficient pentapeptide substrate for the tyrosine kinase pp60c-src .
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Cat. No.: HY-P2372
CAS No.: 131023-24-0
Target:  

Src

Research Areas:  

Others

P60v-src(137-157) is a synthetic peptide that inhibits the tyrosine kinase activity of p60 v-src (IC50: 7.5 μM) .
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Cat. No.: HY-16558R
CAS No.: 487-52-5
Synonyms: 2’,3,4,4’-tetrahydroxy Chalcone (Standard)
Butein (Standard) is the analytical standard of Butein. This product is intended for research and analytical applications. Butein is a cAMP-specific PDE inhibitor with an IC50 of 10.4 μM for PDE4 . Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 μM for EGFR and p60c-src in HepG2 cells . Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a . Butein is a SIRT1 activator (STAC).
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Cat. No.: HY-P3771
CAS No.: 284660-72-6
Target:  

Src

Research Areas:  

Others

p60c-src substrate II,phosphorylated is a pentapeptide. p60c-src substrate II,phosphorylated is a p60c-src substrate II phosphorylated polypeptide. Protein phosphorylation is an important post-translationmodification of protein that is indispensible in biological regulations .
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Cat. No.: HY-P81766
Synonyms: P60 katanin; Katanin P60 subunit A1

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P81766A
Synonyms: P60 katanin; Katanin P60 subunit A1

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P87652
Synonyms: Katanin P60 ATPase-containing subunit A1, Katanin P60 subunit A1, P60 katanin, KATNA1

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human

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