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62 Results for "

PCa

" in MedChemExpress (MCE) Product Catalog:

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MKC8866

17 Publications Verification

Cat. No.: HY-104040

CAS No.: 1338934-59-0

Purity: 99.95%

Synonyms: Orin1001

Target:

IRE1

Research Areas:

Cancer

MKC8866, a salicylaldehyde analog, is a potent, selective IRE1 RNase inhibitor with an IC₅₀ of 0.29 μM in human vitro. MKC8866 strongly inhibits Dithiothreitol-induced X-box-binding protein 1-spliced (XBP1s) expression with an EC₅₀ of 0.52 μM and unstresses RPMI 8226 cells with an IC₅₀ of 0.14 μM . MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibits prostate cancer (PCa) tumor growth .

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Zadavotide guraxetan

3 Cited Publications

Cat. No.: HY-148761

CAS No.: 2192281-54-0

Purity: 99.67%

Synonyms: PSMA I&T; PNT-2002

Target:

PSMA

Research Areas:

Cancer

Zadavotide guraxetan (PSMA I&T; PNT-2002) is an effective inhibitor of prostate-specific membrane antigen (PSMA). Zadavotide guraxetan can be used for SPECT/CT imaging and radionuclide studies in triple-negative breast cancer and prostate cancer (PCa) .

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