17 Results for "

PEPCK

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "PEPCK" in MCE Product Catalog:

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10
10 Cited Publications
Cat. No.: HY-128923
CAS No.: 320386-54-7
Purity:  96.35%
Synonyms: 3-Mercaptopicolinic acid hydrochloride; 3-MPA hydrochloride
Target:  

PEPCK

Research Areas:  

Metabolic Disease

SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor (Ki: 2-9 μM). SKF-34288 hydrochloride is a potent hypoglycemic agent by inhibiting glucose synthesis. SKF-34288 hydrochloride also inhibits Asn metabolism and increases amino acids and amides .
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3
3 Cited Publications
Cat. No.: HY-123046
CAS No.: 1253226-93-5
Purity:  99.44%
Target:  

Autophagy

Research Areas:  

Metabolic Disease Cancer

AS1708727 is an orally active Foxo1 inhibitor, with EC50 values of 0.33 μM and 0.59 μM for G6Pase and PEPCK, respectively .
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Cat. No.: HY-W115752
CAS No.: 10034-93-2
Synonyms: Diamine sulfate (99%)
Hydrazine sulfate is an orally active PEPCK inhibitor. Hydrazine sulfate inhibits PEPCK and low-Km ALDH. Hydrazine sulfate impairs gluconeogenesis and enhances the protective effect of energy substrates against MPP + toxicity. Hydrazine sulfate exacerbates liver damage in rats when combined with Ethanol. Hydrazine sulfate can be used in the research of shock, non-small cell lung cancer, colorectal cancer and Parkinson's disease .
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Cat. No.: HY-N3720
CAS No.: 61854-36-2
Synonyms: 6-Demethoxycapillarisin
Demethoxycapillarisin (6-Demethoxycapillarisin) is a natural polyphenolic compound of the benzochromone class . Demethoxycapillarisin inhibits aldose reductase (ALR2); it also downregulates PEPCK transcription, thereby inhibiting hepatic gluconeogenesis, with an IC50 of 43 µM. Demethoxycapillarisin is an active component with pro-adipogenic activity in Artemisia scoparia, and it is speculated to regulate AMPK through a coumarin-related mechanism. Demethoxycapillarisin can be used in diabetes-related research .
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Cat. No.: HY-W197205
CAS No.: 380173-90-0
Research Areas:  

Metabolic Disease

SL010110 is an anti-hyperglycemic agent. SL010110 potently inhibits gluconeogenesis by inhibiting SIRT2, activating p300, and subsequently promoting PEPCK1 degradation. SL010110 downregulates the protein level of PEPCK1 without affecting the gene expressions of PEPCK, glucose-6-phosphatase, and fructose-1,6-bisphosphatase. SL010110 significantly improves glucose homeostasis in type 2 diabetic (T2D) mice model. SL010110 can be used for T2D research .
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Cat. No.: HY-111896
CAS No.: 113085-62-4
Purity:  98.56%
Synonyms: 7-O-Methoxyrosmanol
7-Methoxyrosmanol (7-O-Methoxyrosmanol), a phenolic diterpene isolated from rosemary, suppresses the cAMP responsiveness of PEPCK and G6Pase promoters .
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Cat. No.: HY-RS17590
Research Areas:  

Others

Pck1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pck1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS10153
Research Areas:  

Others

PCK2 Human Pre-designed siRNA Set A contains three designed siRNAs for PCK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS24050
Research Areas:  

Others

Pck1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Pck1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P84621
Synonyms: PEPCK; PEPCK2; PEPCK-M

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF, FC, ELISA

Reactivity:  

Human, Rat, Monkey

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Cat. No.: HY-P84621A
Synonyms: PEPCK; PEPCK2; PEPCK-M

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF, FC, ELISA

Reactivity:  

Human, Rat, Monkey

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Cat. No.: HY-P80267
Synonyms: PEPCK1, PCK1, PEPCK-C, Serine-protein kinase PCK1

Host:  

Rabbit

Application:  

ICC/IF, IHC-P, WB

Reactivity:  

Human

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Cat. No.: HY-P81802
Synonyms: PCK2; PEPCK2; Phosphoenolpyruvate carboxykinase [GTP]; mitochondrial; PEPCK-M; Phosphoenolpyruvate carboxylase

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P85451
Synonyms: PCK2; PEPCK2; Phosphoenolpyruvate carboxykinase [GTP]; mitochondrial; PEPCK-M; Phosphoenolpyruvate carboxylase

Host:  

Mouse

Application:  

WB

Reactivity:  

Human, Mouse, Rat, Bovine, Dog, Pig

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Cat. No.: HY-P81802A
Synonyms: PCK2; PEPCK2; Phosphoenolpyruvate carboxykinase [GTP]; mitochondrial; PEPCK-M; Phosphoenolpyruvate carboxylase

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-N8250
CAS No.: 928205-59-8
cis-THSG is a selective and orally active DNA topoisomerase II inhibitor with no activity against DNA topoisomerase I. cis-THSG suppresses transcription of PEPCK. cis-THSG reduces blood glucose levels, ameliorates glucose intolerance, and alleviates insulin resistance in high fat diet-induced diabetic male CF-1 mice. cis-THSG can be used for the research of type 2 diabetes mellitus .
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Cat. No.: HY-P75957
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PCK2; MtPCK2; Phosphoenolpyruvate Carboxykinase 2, Mitochondrial; Phosphoenolpyruvate Carboxykinase 2 (Mitochondrial); PEPCK2; Phosphoenolpyruvate Carboxykinase 2 Isoform 3; Phosphoenolpyruvate Carboxykinase [GTP], Mitochondrial; Epididymis Secretory Sper
Species:  
Human
Source:  
Sf9 insect cells
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