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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
PF07257876
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "PF07257876" in MCE Product Catalog:
Cat. No.: HY-P992553
Target:
Research Areas:
PF-07257876 is a CD47/PD‑L1 bispecific antibody that preferentially targets tumor cells through high PD-L1 affinity and weak CD47 affinity . PF‑07257876 simultaneously blocks the CD47‑SIRPα innate immune checkpoint and the PD‑L1/PD‑1 adaptive immune checkpoint, activates dendritic cells and macrophages, enhances CD8 + T cell infiltration within the tumor microenvironment, and synergistically mobilizes innate and adaptive immunity to exert antitumor effects . PF-07257876 can be used in research on CD47/PD‑L1-related cancers, such as ovarian cancer and non-small cell lung cancer .
Cat. No.: HY-P992554
Target:
Research Areas:
PF-08046032 Antibody represents the antibody component of PF-07257876 (HY-P992553). PF-07257876 is a bispecific antibody targeting CD47/PD-L1; it simultaneously blocks the CD47-SIRPα innate immune checkpoint and the PD-L1/PD-1 adaptive immune checkpoint, synergistically mobilizing both innate and adaptive immunity to exert anti-tumor effects .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
