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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Pantetheinase
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Pantetheinase" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-18780
CAS No.: 1351758-37-6
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RR6 is a potent, selective, reversible, competitive and orally active vanin inhibitor with an IC50 of 540 nM for recombinant vanin-1. RR6 also potently inhibits human, bovine and rat serum pantetheinase with IC50 values of 40 nM, 41 nM and 87 nM, respectively .
Synonyms: Vanin-1-IN-1
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PFI-653 (Vanin-1-IN-1, compound 3), a chemical probe, is a vanin-1 inhibitor that binds to plasma vanin-1 from mouse, rat, dog, and human. Vanin-1 is a cell surface-associated inositol (GPi) -anchored protein that plays important roles in metabolism and inflammation. PFI-653 inhibits vanin-1 from different species with IC50s of 6.85 nM (human recombinant plasma vanin-1), 9.0 nM (human plasma vanin-1), 24.5 nM (mouse recombinant vanin-1), and 53.4 nM (mouse plasma vanin-1) .
Cat. No.: HY-69142
CAS No.: 374068-01-6
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2-Chloropyrimidine-5-carboxylic acid is a synthetic intermediate of Vanin-1 inhibitor 2 .
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Vanin-1-IN-3 (OMP-7) is a vanin-1 inhibitor with an IC50 of 0.038 μM .
Cat. No.: HY-159986
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X-17 is a Vanin-1 Inhibitor with potent anti-inflammatory and antioxidant activities. X-17 repressrs the inflammatory factor expressions and myeloperoxidase activity, elevats the colonic glutathione reserve, and restors the intestinal barrier .
Cat. No.: HY-145316
CAS No.: 2054952-13-3
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Vanin-1-IN-2 is a potent vanin-1 inhibitor with an IC50 of 162 nM. Vanin-1 is a cell-surface-associated, glycosylphosphatidyl inositol (GPI)-anchored protein which is expressed at high levels in the kidney, liver, and small intestine .
Cat. No.: HY-161249
CAS No.: 2173134-02-4
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Vanin-1-IN-4 (compound (S)-1) is vanin-1 inhibitor with a chiral methyl substituent, with profils as potent drug-candidate but exist as an amorphous solid .
Cat. No.: HY-149594
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CL-Pa is a chemiluminescent probe suitable for detection of urinary Vanin-1. CL-Pa can be used to detect drug-induced acute kidney injury (AKI) through urinalysis .
Cat. No.: HY-187888
CAS No.: 2254498-21-8
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Vanin-1-IN-6 (Compound Ex. 26) is a potent Vanin-1 inhibitor with an IC50 of 0.2 nM. Vanin-1-IN-6 reduces cysteamine production by inhibiting the Vanin-1 enzyme, preventing oxidative stress caused by glutathione depletion, thereby alleviating tissue damage and inflammation. Vanin-1-IN-6 can be used in research on Vanin-related diseases (Crohn's disease, inflammation, and autoimmune diseases) .
Cat. No.: HY-N1220
CAS No.: 33116-33-5
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Stephavanine is a compound isolated from the roots of Stephania abyssinica .
Cat. No.: HY-P71045
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VNN2; Vanin 2; FOAP-4; GPI-80; Glycosylphosphatidyl Inositol-Anchored Protein GPI-80; Vascular Non-Inflammatory Molecule 2; Pantetheine Hydrolase VNN2; Pantetheinase; cDNA FLJ55137, Highly Similar To Vascular Non-Inflammatory Molecule 2; Protein FOAP-4; Vannin 2; Vanin-2
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
