9 Results for "

QR2

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "QR2" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-122614
CAS No.: 874484-20-5
Purity:  99.29%
Synonyms: NMDPEF
Target:  

Autophagy

Research Areas:  

Neurological Disease

S29434 (NMDPEF) is a potent, competitive, selective and cell-permeable inhibitor of quinone reductase 2 (QR2), with IC50s ranging from 5 to 16 nM for human QR2 at different organizational levels, and has good selectivity for QR2 over QR1. S29434 induces autophagy and inhibits QR2-mediated ROS production .
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1
1 Cited Publications
Cat. No.: HY-N1066
CAS No.: 274675-25-1
Xanthohumol D, isolated from hops, is an inhibitor of quinone reductase-2 (QR-2) with the IC50 value of 110 μM, and binds to the active site of QR-2. Xanthohumol D shows antiproliferative activity on human cancer cell lines in vitro [2].
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Cat. No.: HY-N12326
CAS No.: 1350028-90-8
Multiflorin A is an orally active active ingredient of traditional herbal laxative, Pruni semen. Multiflorin A inhibits aromatase enzyme activity with an IC50 of 15.5 μM. Multiflorin A also inhibits quinone reductase 2 (QR2) and COX-2 enzyme. Multiflorin A has purgative activity and reduces postprandial blood glucose in mice. Multiflorin A modulates intestinal glucose transporters, tight junction proteins, and aquaporins, reshapes gut microbiota, and alters faecal metabolites. Multiflorin A can be used for the research of constipation and diabetes [2].
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Cat. No.: HY-144635
CAS No.: 3035124-25-2
Purity:  98.44%
Nrf2-ARE/hMAO-B/QR2 modulator 1 is a Resveratrol-based multitarget-directed ligands with IC50s of 8.05, 9.83 and 0.57 μM for hMAO-B, NRF2 and QR2. Nrf2-ARE/hMAO-B/QR2 modulator 1 has neuroprotection, decreasing ROS production in okadaic acid-treated mice hippocampal slices . Nrf2-ARE/hMAO-B/QR2 modulator 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-P82542
Synonyms: QR2; DHQV; DIA6; NMOR2

Host:  

Rabbit

Application:  

WB, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-N11855
CAS No.: 477-89-4
Casimiroin is a QR2 and Aromatase inhibitor, with an IC50 of 54.1 μM against QR2 and an IC50 of 3.92 μM against aromatase. Casimiroin exhibits antimutagenic activity and inhibits DMBA (HY-W011845)-induced mutations in Salmonella typhimurium. Casimiroin suppresses DMBA-induced precancerous lesions in mouse mammary organ cultures. Casimiroin can be used in breast cancer-related research [2].
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Cat. No.: HY-RS09524
Research Areas:  

Others

NQO2 Human Pre-designed siRNA Set A contains three designed siRNAs for NQO2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P706327
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Ribosyldihydronicotinamide dehydrogenase; NRH dehydrogenase 2; NRH:quinone oxidoreductase 2; Quinone reductase 2 (QR2); Nqo2; Nmor2
Species:  
Mouse
Source:  
E. coli
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Cat. No.: HY-P706330
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Ribosyldihydronicotinamide dehydrogenase; NRH dehydrogenase 2; NRH:quinone oxidoreductase 2; Quinone reductase 2 (QR2); Nqo2; Nmor2
Species:  
Human
Source:  
E. coli
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